Nucleophilic addition of phosphine to 4-chlorostyrenes in the KOH-DMSO system
In the superbasic system KOH-DMSO (H 2 O) at 60–75 °C (2–2.5 h, atmospheric pressure), 4-chlorostyrene and 4-chloro-α-methylstyrene add phosphine at the double bond to form 1: 1 and 2: 1 anti-Markovnikov adducts in 10–18% and 58–67% yields, respectively.
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Published in | Russian chemical bulletin Vol. 62; no. 11; pp. 2495 - 2497 |
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Main Authors | , , , , , |
Format | Journal Article |
Language | English |
Published |
Boston
Springer US
01.11.2013
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Subjects | |
Online Access | Get full text |
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