Aberrant DNA methylation in lymphocytes of children with neurodevelopmental disorders

• Published in: Russian journal of genetics Vol. 53; no. 11; pp. 1243 - 1258
• Main Authors: Naumova, O. Yu, Rychkov, S. Yu, Odintsova, V. V., Kornilov, S. A., Shabalina, E. V., Antsiferova, D. V., Zhukova, O. V., Grigorenko, E. L.
• Format: Journal Article
• Language: English
• Published: Moscow Pleiades Publishing 01.11.2017
• Subjects: Animal Genetics and Genomics; Biomedical and Life Sciences; Biomedicine; Human Genetics; Microbial Genetics and Genomics; peripheral blood lymphocytes; genome-wide DNA methylation; Illumina HumanMethylation450; encephalopathy; differential methylation; epigenetics

Recent research in the field of genomics and epigenetics has provided evidence that alterations in the system of epigenetic regulation are highly involved in the molecular etiology of neurodegenerative and neuropathic disorders. However, there is a gap in knowledge on the epigenetic perturbations th...