Comparison of Enzyme Immunoassay and Latex Agglutination Methods for Detection of Cryptococcus neoformans Antigen

• Published in: American journal of clinical pathology Vol. 73; no. 6; pp. 790 - 794
• Main Authors: Scott, E. Nan, Muchmore, Harold G., Felton, Frances G.
• Format: Journal Article
• Language: English
• Published: England 01.06.1980
• Subjects: Antigens, Fungal - analysis; Cryptococcosis - diagnosis; Cryptococcus - immunology; Cryptococcus neoformans - immunology; Enzyme-Linked Immunosorbent Assay; Humans; Immunoenzyme Techniques; Latex Fixation Tests

An enzyme immunoassay for the measurement of cryptococcal capsular polysaccharide in human body fluids is described. The enzyme immunoassay detects cryptococcal capsular polysaccharide at a concentration of 6 ng/ml, compared with 35 ng/ml detectable by the latex agglutination test. The enzyme immuno...