Functional importance of ventricular enlargement and cortical atrophy in healthy subjects and alcoholics as assessed with PET, MR imaging, and neuropsychologic testing

• Published in: Radiology Vol. 186; no. 1; p. 59
• Main Authors: Wang, G J, Volkow, N D, Roque, C T, Cestaro, V L, Hitzemann, R J, Cantos, E L, Levy, A V, Dhawan, A P
• Format: Journal Article
• Language: English
• Published: United States 01.01.1993
• Subjects: Adult; Alcoholism - diagnostic imaging; Alcoholism - metabolism; Alcoholism - pathology; Alcoholism - psychology; Atrophy; Brain - diagnostic imaging; Brain - metabolism; Brain - pathology; Cerebral Cortex - diagnostic imaging; Cerebral Cortex - pathology; Cerebral Ventricles - diagnostic imaging; Cerebral Ventricles - pathology; Deoxyglucose - analogs & derivatives; Fluorodeoxyglucose F18; Glucose - metabolism; Humans; Magnetic Resonance Imaging; Male; Middle Aged; Neuropsychological Tests; Reference Values; Tomography, Emission-Computed

The authors assessed the relationship between ventricular enlargement, cortical atrophy, regional brain glucose metabolism, and neuropsychologic performance in 10 alcoholics and 10 control subjects. Regional brain glucose metabolism was measured with fluorine-18 fluorodeoxyglucose (FDG) and positron...