Evaluation of In Vitro α‐Amylase and α‐Glucosidase Inhibitory Potentials of 14 Medicinal Plants Constituted in Thai Folk Antidiabetic Formularies
The sporadic increase in the occurrence and prevalence of diabetes mellitus have compelled and vigorous search for alternative anti‐diabetic therapeutic approach from medicinal plants and its bioactive. One of the major approach employed is the reduction of gastrointestinal glucose levels through th...
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| Published in | Chemistry & biodiversity Vol. 15; no. 4; pp. e1800025 - n/a |
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| Language | English |
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| Abstract | The sporadic increase in the occurrence and prevalence of diabetes mellitus have compelled and vigorous search for alternative anti‐diabetic therapeutic approach from medicinal plants and its bioactive. One of the major approach employed is the reduction of gastrointestinal glucose levels through the inhibition of carbohydrate digesting enzymes notably α‐amylase and α‐glucosidase. In this study, the ethanol extracts of 14 selected plants from Mor Porn's recipe were screened for their α‐amylase and α‐glucosidase inhibitory activity. The ethanolic extract from the stem of Vitex glabrata displayed the highest percentage inhibitory activity of 84.98 ± 0.59 and 84.71 ± 1.51 against α‐glucosidase and α‐amylase enzymes, respectively. Chemical investigation of the active extract of V. glabrata indicated that pentacyclic triterpenes were the major compounds responsible for the activity. The result obtained from this study suggests the potential use of V. glabrata as an alternative natural source for the treatment of diabetes mellitus. |
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| AbstractList | The sporadic increase in the occurrence and prevalence of diabetes mellitus have compelled and vigorous search for alternative anti-diabetic therapeutic approach from medicinal plants and its bioactive. One of the major approach employed is the reduction of gastrointestinal glucose levels through the inhibition of carbohydrate digesting enzymes notably α-amylase and α-glucosidase. In this study, the ethanol extracts of 14 selected plants from Mor Porn's recipe were screened for their α-amylase and α-glucosidase inhibitory activity. The ethanolic extract from the stem of Vitex glabrata displayed the highest percentage inhibitory activity of 84.98 ± 0.59 and 84.71 ± 1.51 against α-glucosidase and α-amylase enzymes, respectively. Chemical investigation of the active extract of V. glabrata indicated that pentacyclic triterpenes were the major compounds responsible for the activity. The result obtained from this study suggests the potential use of V. glabrata as an alternative natural source for the treatment of diabetes mellitus. The sporadic increase in the occurrence and prevalence of diabetes mellitus have compelled and vigorous search for alternative anti‐diabetic therapeutic approach from medicinal plants and its bioactive. One of the major approach employed is the reduction of gastrointestinal glucose levels through the inhibition of carbohydrate digesting enzymes notably α ‐amylase and α ‐glucosidase. In this study, the ethanol extracts of 14 selected plants from Mor Porn's recipe were screened for their α ‐amylase and α ‐glucosidase inhibitory activity. The ethanolic extract from the stem of Vitex glabrata displayed the highest percentage inhibitory activity of 84.98 ± 0.59 and 84.71 ± 1.51 against α ‐glucosidase and α ‐amylase enzymes, respectively. Chemical investigation of the active extract of V. glabrata indicated that pentacyclic triterpenes were the major compounds responsible for the activity. The result obtained from this study suggests the potential use of V. glabrata as an alternative natural source for the treatment of diabetes mellitus. The sporadic increase in the occurrence and prevalence of diabetes mellitus have compelled and vigorous search for alternative anti‐diabetic therapeutic approach from medicinal plants and its bioactive. One of the major approach employed is the reduction of gastrointestinal glucose levels through the inhibition of carbohydrate digesting enzymes notably α‐amylase and α‐glucosidase. In this study, the ethanol extracts of 14 selected plants from Mor Porn's recipe were screened for their α‐amylase and α‐glucosidase inhibitory activity. The ethanolic extract from the stem of Vitex glabrata displayed the highest percentage inhibitory activity of 84.98 ± 0.59 and 84.71 ± 1.51 against α‐glucosidase and α‐amylase enzymes, respectively. Chemical investigation of the active extract of V. glabrata indicated that pentacyclic triterpenes were the major compounds responsible for the activity. The result obtained from this study suggests the potential use of V. glabrata as an alternative natural source for the treatment of diabetes mellitus. |
| Author | Ovatlarnporn, Chitchamai Somtimuang, Chonlatid Olatunji, Opeyemi Joshua |
| Author_xml | – sequence: 1 givenname: Chonlatid surname: Somtimuang fullname: Somtimuang, Chonlatid email: chonlatid.s@psu.ac.th organization: Prince of Songkla University – sequence: 2 givenname: Opeyemi Joshua surname: Olatunji fullname: Olatunji, Opeyemi Joshua organization: Prince of Songkla University – sequence: 3 givenname: Chitchamai surname: Ovatlarnporn fullname: Ovatlarnporn, Chitchamai organization: Prince of Songkla University |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/29460340$$D View this record in MEDLINE/PubMed |
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| Cites_doi | 10.1016/j.biopha.2016.05.036 10.1039/a902202c 10.2337/diacare.12.8.553 10.1046/j.1432-1327.1998.2560238.x 10.1016/j.foodchem.2013.04.123 10.1039/c0np00059k 10.2337/diacare.27.5.1047 10.1016/j.bmc.2004.12.010 10.1007/s11892-016-0725-7 10.6026/97320630010209 10.1016/S0040-4020(01)87309-9 10.3810/pgm.2012.11.2615 10.1080/14786419.2011.560849 10.9734/IJTDH/2012/1693 10.1007/s11418-007-0184-1 10.1016/j.ejps.2006.04.006 10.1007/s11418-009-0343-7 10.1002/cbdv.201700277 10.1016/j.diabres.2011.10.029 10.1016/S0040-4020(98)01030-8 10.1016/j.biopha.2016.10.002 10.1016/j.bmcl.2017.04.078 10.5772/27253 10.1271/bbb.64.1041 10.1023/B:MCBI.0000028738.95518.90 10.1016/j.jep.2010.11.038 10.1186/1744-8603-9-11 10.1007/BF02976955 10.1016/j.bioorg.2017.09.003 10.1007/BF00483562 10.1016/j.jep.2014.02.042 10.1016/j.bmcl.2006.09.051 10.1002/ptr.5525 10.1016/j.fct.2008.08.020 10.1021/np9006298 10.1590/S0103-50532004000300008 10.1007/978-3-642-60250-4_1 10.2165/00003495-199200443-00007 10.5897/AJPP12.1304 10.3390/nu9020163 10.1023/A:1014910132595 10.1021/jf1045359 |
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| Keywords | Vitex glabrata R.Br Mor Porn's recipe α-glucosidase α-amylase anti-diabetic diabetes |
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| References | 2007; 17 2009; 63 2012; 124 2012 2002; 153 2004; 27 1997; 64 2017; 27 2004; 261 2002; 13 2000; 64 2016; 30 2013; 141 2011; 59 2011; 3 2016; 16 1998; 256 2014; 153 2017; 9 2013; 9 2001; 133 2017; 75 2012; 2 1989; 12 2010; 24 2000; 17 2017; 14 1986; 42 2000 2009; 72 2004; 15 2011; 94 2005; 5 1999; 55 2006; 29 2003; 26 2016; 84 2008; 46 2016; 82 2012; 26 2012; 25 2012; 6 2011; 28 2008; 62 2010; 2 1992; 44 2005; 13 2014; 10 e_1_2_8_28_1 Bachhawat A. (e_1_2_8_48_1) 2011; 3 Aryangat A. V. (e_1_2_8_10_1) 2010; 24 e_1_2_8_29_1 e_1_2_8_47_1 e_1_2_8_25_1 e_1_2_8_46_1 e_1_2_8_26_1 e_1_2_8_49_1 e_1_2_8_27_1 Meena A. K. (e_1_2_8_19_1) 2010; 2 e_1_2_8_3_1 e_1_2_8_2_1 e_1_2_8_5_1 e_1_2_8_4_1 e_1_2_8_7_1 e_1_2_8_6_1 e_1_2_8_9_1 e_1_2_8_8_1 e_1_2_8_20_1 e_1_2_8_43_1 e_1_2_8_21_1 e_1_2_8_42_1 e_1_2_8_22_1 e_1_2_8_45_1 e_1_2_8_23_1 e_1_2_8_44_1 e_1_2_8_41_1 e_1_2_8_40_1 e_1_2_8_18_1 e_1_2_8_39_1 e_1_2_8_13_1 e_1_2_8_36_1 e_1_2_8_14_1 e_1_2_8_35_1 e_1_2_8_15_1 e_1_2_8_38_1 e_1_2_8_16_1 e_1_2_8_37_1 Chouhan C. S. (e_1_2_8_24_1) 2012; 25 Lin L.‐C. (e_1_2_8_33_1) 2002; 13 Ganapaty S. (e_1_2_8_17_1) 2005; 5 e_1_2_8_32_1 e_1_2_8_31_1 e_1_2_8_11_1 e_1_2_8_34_1 e_1_2_8_12_1 e_1_2_8_30_1 |
| References_xml | – volume: 27 start-page: 1047 year: 2004 end-page: 1053 article-title: Global Prevalence of Diabetes: Estimates for the Year 2000 and Projections for 2030 publication-title: Diabetes Care – volume: 14 start-page: e1700277 year: 2017 article-title: Effect of the Polyphenol Rich Ethyl Acetate Fraction from the Leaves of . on Oxidative Stress, Dyslipidemia, and Diabetes Mellitus in Streptozotocin‐Nicotinamide Induced Diabetic Rats publication-title: Chem. Biodiversity – volume: 44 start-page: 47 year: 1992 end-page: 53 article-title: Safety Profile of Acarbose, an ‐Glucosidase Inhibitor publication-title: Drugs – volume: 63 start-page: 393 year: 2009 end-page: 401 article-title: Hypoglycemic Activity of Constituents from in Normal and Streptozotocin‐Induced Diabetic Mice publication-title: J. Nat. Med. – volume: 141 start-page: 2170 year: 2013 end-page: 2176 article-title: The ‐Amylase and ‐Glucosidase Inhibitory Effects of Irish Seaweed Extracts publication-title: Food Chem. – volume: 13 start-page: 191 year: 2002 end-page: 195 article-title: Constituents from the Stems of publication-title: J. Chin. Med. – volume: 153 start-page: 392 year: 2014 end-page: 399 article-title: Anti‐Diabetic Effects of the Acetone Fraction of Stem Bark in a Type 2 Diabetes Rat Model publication-title: J. Etnopharmacol. – volume: 30 start-page: 260 year: 2016 end-page: 266 article-title: Medicinal Plants Traditionally Used for Treatment of Obesity and Diabetes Mellitus – Screening for Pancreatic Lipase and ‐Amylase Inhibition publication-title: Phytother. Res. – volume: 3 start-page: 267 year: 2011 end-page: 274 article-title: Screening of Fifteen Indian Ayurvedic Plants for Alpha‐Glucosidase Inhibitory Activity and Enzyme Kinetics publication-title: Int. J. Pharm. Pharm. Sci. – start-page: 487 year: 2012 end-page: 502 – volume: 46 start-page: 3458 year: 2008 end-page: 3466 article-title: Antidiabetic Activity of 50% Ethanolic Extract of and Its Purified Fractions publication-title: Food Chem. Toxicol. – volume: 15 start-page: 385 year: 2004 end-page: 394 article-title: Phytochemistry of a, , and : Chemosystematic Implications publication-title: J. Braz. Chem. Soc. – volume: 9 start-page: 163 year: 2017 article-title: Cinnamic Acid and Its Derivatives: Mechanisms for Prevention and Management of Diabetes and Its Complications publication-title: Nutrients – volume: 29 start-page: 1 year: 2006 end-page: 13 article-title: Pharmacological Properties of the Ubiquitous Natural Product Betulin publication-title: Eur. J. Pharm. Sci. – volume: 133 start-page: 1091 year: 2001 end-page: 1095 article-title: Hypoglycemic Evaluation of a New Triterpene and Other Compound Isolated from Thunb. var. (Ebenacea) Root Bark publication-title: J. Ethnopharmacol. – volume: 9 start-page: 1 year: 2013 end-page: 18 article-title: Diabetes Management in Thailand: A Literature Review of the Burden, Costs, and Outcomes publication-title: Global. Health – volume: 24 start-page: 145 year: 2010 end-page: 155 article-title: Type 2 Diabetes: Postprandial Hyperglycemia and Increased Cardiovascular Risk publication-title: Vasc. Health Risk Manag. – volume: 12 start-page: 553 year: 1989 end-page: 564 article-title: Traditional Plant Medicines as Treatments for Diabetes publication-title: Diabetes Care – volume: 62 start-page: 47 year: 2008 end-page: 51 article-title: Two New Lignan Glucosides from the Fruit of publication-title: J. Nat. Med. – volume: 6 start-page: 3230 year: 2012 end-page: 3234 article-title: Antioxidant and ‐Glucosidase Inhibitory Compounds in publication-title: Afr. J. Pharm. Pharmacol. – volume: 5 start-page: 75 year: 2005 end-page: 95 article-title: Phytoconstituents and Biological Activities of – A Review publication-title: J. Nat. Rem. – volume: 2 start-page: 01 year: 2010 end-page: 09 article-title: Pharmacological and Phytochemical Evidences for the Extracts from Plants of the Genus Vitex – A Review publication-title: Int. J. Pharm. Clin. Res. – volume: 27 start-page: 2818 year: 2017 end-page: 2823 article-title: Synthesis and ‐Glucosidase Inhibition Activity of Dihydroxy Pyrrolidines publication-title: Bioorg. Med. Chem. Lett. – volume: 13 start-page: 1661 year: 2005 end-page: 1671 article-title: ‐Glucosidase Inhibition of 6‐Hydroxyflavones. Part 3: Synthesis and Evaluation of 2,3,4‐Trihydroxybenzoyl‐Containing Flavonoid Analogs and 6‐Aminoflavones as ‐Glucosidase Inhibitors publication-title: Bioorg. Med. Chem. – volume: 25 start-page: 131 year: 2012 end-page: 134 article-title: Anti‐Inflammatory Activity of Ethanol Extract of Leaves publication-title: Pak. J. Pharm. Sci. – volume: 64 start-page: 536 year: 1997 end-page: 537 article-title: Glucosidase Inhibition. A New Approach to the Treatment of Diabetes, Obesity, and Hyperlipoproteinaemia publication-title: Naturwissenschaften – volume: 59 start-page: 2324 year: 2011 end-page: 2331 article-title: Berry Polyphenols Inhibit ‐Amylase : Identifying Active Components in Rowanberry and Raspberry publication-title: J. Agric. Food Chem. – volume: 261 start-page: 63 year: 2004 end-page: 70 article-title: Beneficial Effects and Mechanism of Action of Juice in the Treatment of Streptozotocin‐Induced Diabetes Mellitus in Rat publication-title: Mol. Cell. Biochem. – volume: 64 start-page: 1041 year: 2000 end-page: 1043 article-title: ‐Amylase Inhibitors from Roselle ( Linn.) Tea publication-title: Biosci. Biotechnol. Biochem. – volume: 72 start-page: 1954 year: 2009 end-page: 1959 article-title: Antiestrogenic Constituents of the Thai Medicinal Plants and publication-title: J. Nat. Prod. – volume: 17 start-page: 239 year: 2007 end-page: 242 article-title: New Antifungal Flavonoid Glycosides from publication-title: Bioorg. Med. Chem. Lett. – volume: 42 start-page: 3419 year: 1986 end-page: 3428 article-title: Total Assignment of C and H Spectra of Three Isomeric Triterpenol Derivatives by 2D NMR: An Investigation of the Potential Utility of H Chemical Shifts in Structural Investigation of Complex Natural Products publication-title: Tetrahedron – volume: 94 start-page: 311 year: 2011 end-page: 332 article-title: IDF Diabetes Atlas: Global Estimate of the Prevalence of Diabetes for 2011 and 2030 publication-title: Diabetes Res. Clin. Pract. – volume: 26 start-page: 275 year: 2003 end-page: 278 article-title: A New Acylglycosyl Sterol from publication-title: Arch. Pharmacal Res. – volume: 153 start-page: 199 year: 2002 end-page: 202 article-title: Isolation of Scopoletin from Leaves of and the Effect of Scopoletin on Pathogens of publication-title: Mycopathologia – volume: 17 start-page: 215 year: 2000 end-page: 234 article-title: The Influence of Natural Products Upon Drug Discovery publication-title: Nat. Prod. Rep. – volume: 26 start-page: 1135 year: 2012 end-page: 1140 article-title: Antioxidant and Hepatoprotective Effects of Ethanol Extract of on Carbon Tetrachloride‐Induced Liver Damage in Rats publication-title: Nat. Prod. Res. – volume: 256 start-page: 238 year: 1998 end-page: 244 article-title: ‐Amyrin Synthase – Cloning of Oxidosqualene Cyclase That Catalyzes the Formation of the Most Popular Triterpene Among Higher Plants publication-title: Eur. J. Biochem. – volume: 124 start-page: 90 year: 2012 end-page: 97 article-title: Chronic Hyperglycemia and Glucose Toxicity: Pathology and Clinical Sequelae publication-title: Postgrad. Med. – volume: 28 start-page: 543 year: 2011 end-page: 593 article-title: Synthesis, Biology and Clinical Significance of Pentacyclic Triterpenes: A Multi‐Target Approach to Prevention and Treatment of Metabolic and Vascular Diseases publication-title: Nat. Prod. Rep. – volume: 16 start-page: 28 year: 2016 article-title: Diabetes in Thailand: Status and Policy publication-title: Curr. Diab. Rep. – volume: 55 start-page: 255 year: 1999 end-page: 260 article-title: Regioselective Synthesis of 24‐ ‐Pterosterone publication-title: Tetrahedron – volume: 75 start-page: 99 year: 2017 end-page: 105 article-title: Synthesis of Thiobarbituric Acid Derivatives: ‐Glucosidase Inhibition and Molecular Docking Studies publication-title: Bioorg. Chem. – volume: 10 start-page: 209 year: 2014 end-page: 215 article-title: Molecular Modeling of L Compounds as ‐Amylase Inhibitor: An Comparation Between Human and Rat Enzyme Model publication-title: Bioinformation – volume: 2 start-page: 290 year: 2012 end-page: 300 article-title: Anti‐Diabetic Activity of Aqueous Extracts of Vitex Donilana Leaves and Cinchona Calisaya Bark in Alloxan‐Induced Diabetic Rats publication-title: Int. J. Trop. Dis. Health – volume: 84 start-page: 1472 year: 2016 end-page: 1487 article-title: Anti‐Diabetic Activity of Saponin publication-title: Biomed. Pharmacother. – volume: 82 start-page: 547 year: 2016 end-page: 554 article-title: Antidiabetic Activity of in Streptozotocin‐Nicotinamide Induced Type‐2 Diabetic Rats publication-title: Biomed. Pharmacother. – start-page: 3 year: 2000 end-page: 37 – ident: e_1_2_8_15_1 doi: 10.1016/j.biopha.2016.05.036 – ident: e_1_2_8_35_1 doi: 10.1039/a902202c – ident: e_1_2_8_14_1 doi: 10.2337/diacare.12.8.553 – volume: 2 start-page: 01 year: 2010 ident: e_1_2_8_19_1 article-title: Pharmacological and Phytochemical Evidences for the Extracts from Plants of the Genus Vitex – A Review publication-title: Int. J. Pharm. Clin. Res. contributor: fullname: Meena A. K. – ident: e_1_2_8_29_1 doi: 10.1046/j.1432-1327.1998.2560238.x – ident: e_1_2_8_44_1 doi: 10.1016/j.foodchem.2013.04.123 – volume: 25 start-page: 131 year: 2012 ident: e_1_2_8_24_1 article-title: Anti‐Inflammatory Activity of Ethanol Extract of Vitex glabrata Leaves publication-title: Pak. J. Pharm. Sci. contributor: fullname: Chouhan C. S. – ident: e_1_2_8_46_1 doi: 10.1039/c0np00059k – ident: e_1_2_8_5_1 doi: 10.2337/diacare.27.5.1047 – ident: e_1_2_8_37_1 doi: 10.1016/j.bmc.2004.12.010 – ident: e_1_2_8_9_1 doi: 10.1007/s11892-016-0725-7 – ident: e_1_2_8_42_1 doi: 10.6026/97320630010209 – ident: e_1_2_8_26_1 doi: 10.1016/S0040-4020(01)87309-9 – ident: e_1_2_8_11_1 doi: 10.3810/pgm.2012.11.2615 – volume: 5 start-page: 75 year: 2005 ident: e_1_2_8_17_1 article-title: Phytoconstituents and Biological Activities of Vitex – A Review publication-title: J. Nat. Rem. contributor: fullname: Ganapaty S. – volume: 24 start-page: 145 year: 2010 ident: e_1_2_8_10_1 article-title: Type 2 Diabetes: Postprandial Hyperglycemia and Increased Cardiovascular Risk publication-title: Vasc. Health Risk Manag. contributor: fullname: Aryangat A. V. – ident: e_1_2_8_25_1 doi: 10.1080/14786419.2011.560849 – volume: 13 start-page: 191 year: 2002 ident: e_1_2_8_33_1 article-title: Constituents from the Stems of Ecdysanthera rosea publication-title: J. Chin. Med. contributor: fullname: Lin L.‐C. – ident: e_1_2_8_21_1 doi: 10.9734/IJTDH/2012/1693 – ident: e_1_2_8_18_1 doi: 10.1007/s11418-007-0184-1 – ident: e_1_2_8_30_1 doi: 10.1016/j.ejps.2006.04.006 – ident: e_1_2_8_47_1 doi: 10.1007/s11418-009-0343-7 – ident: e_1_2_8_2_1 doi: 10.1002/cbdv.201700277 – ident: e_1_2_8_4_1 doi: 10.1016/j.diabres.2011.10.029 – ident: e_1_2_8_23_1 doi: 10.1016/S0040-4020(98)01030-8 – ident: e_1_2_8_3_1 doi: 10.1016/j.biopha.2016.10.002 – ident: e_1_2_8_34_1 doi: 10.1016/j.bmcl.2017.04.078 – volume: 3 start-page: 267 year: 2011 ident: e_1_2_8_48_1 article-title: Screening of Fifteen Indian Ayurvedic Plants for Alpha‐Glucosidase Inhibitory Activity and Enzyme Kinetics publication-title: Int. J. Pharm. Pharm. Sci. contributor: fullname: Bachhawat A. – ident: e_1_2_8_28_1 doi: 10.5772/27253 – ident: e_1_2_8_49_1 doi: 10.1271/bbb.64.1041 – ident: e_1_2_8_12_1 doi: 10.1023/B:MCBI.0000028738.95518.90 – ident: e_1_2_8_41_1 doi: 10.1016/j.jep.2010.11.038 – ident: e_1_2_8_8_1 doi: 10.1186/1744-8603-9-11 – ident: e_1_2_8_31_1 doi: 10.1007/BF02976955 – ident: e_1_2_8_38_1 doi: 10.1016/j.bioorg.2017.09.003 – ident: e_1_2_8_39_1 doi: 10.1007/BF00483562 – ident: e_1_2_8_16_1 doi: 10.1016/j.jep.2014.02.042 – ident: e_1_2_8_20_1 doi: 10.1016/j.bmcl.2006.09.051 – ident: e_1_2_8_45_1 doi: 10.1002/ptr.5525 – ident: e_1_2_8_7_1 doi: 10.1016/j.fct.2008.08.020 – ident: e_1_2_8_22_1 doi: 10.1021/np9006298 – ident: e_1_2_8_27_1 doi: 10.1590/S0103-50532004000300008 – ident: e_1_2_8_36_1 doi: 10.1007/978-3-642-60250-4_1 – ident: e_1_2_8_13_1 doi: 10.2165/00003495-199200443-00007 – ident: e_1_2_8_40_1 doi: 10.5897/AJPP12.1304 – ident: e_1_2_8_6_1 doi: 10.3390/nu9020163 – ident: e_1_2_8_32_1 doi: 10.1023/A:1014910132595 – ident: e_1_2_8_43_1 doi: 10.1021/jf1045359 |
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| SubjectTerms | Amylases Antidiabetics anti‐diabetic Carbohydrates Diabetes Diabetes mellitus Enzymes Ethanol Glucosidase Herbal medicine Medicinal plants Mor Porn's recipe Plant extracts Plants (botany) Triterpenes Vitex glabrata R.Br α-Amylase α-Glucosidase |
| Title | Evaluation of In Vitro α‐Amylase and α‐Glucosidase Inhibitory Potentials of 14 Medicinal Plants Constituted in Thai Folk Antidiabetic Formularies |
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