Spermatogonial stem cell transplantation, testicular function, and restoration of male fertility in mice

• Published in: Methods in molecular biology (Clifton, N.J.) Vol. 450; p. 149
• Main Author: McLean, Derek J
• Format: Journal Article
• Language: English
• Published: United States 2008
• Subjects: Adult Stem Cells - transplantation; Animals; Cell Separation; Fertility - physiology; Male; Mice; Mice, Inbred C57BL; Mice, Mutant Strains; Mice, Transgenic; Spermatogenesis - physiology; Spermatogonia - transplantation; Testis - cytology; Testis - physiology

Mammalian spermatogonial stem cells, sometimes called male germline stem cells, are a small population of adult tissue-specific stem cells present in the testis. Formation of the spermatogonial stem cell population early in life and differentiation of spermatogonial stem cells in adults are responsi...