The role of molecular biomarkers for predicting adjacent breast cancer of Atypical Ductal Hyperplasia diagnosed on core biopsy

• Published in: Cancer biomarkers : section A of Disease markers Vol. 17; no. 3; pp. 293 - 300
• Main Authors: Polat, Ayfer Kamali, Soran, Atilla, Kanbour-Shakir, Amal, Menekse, Ebru, Levent Balci, Fatih, Johnson, Ronald
• Format: Journal Article
• Language: English
• Published: Netherlands 26.09.2016
• Subjects: Biomarkers; Biopsy, Large-Core Needle; Breast Neoplasms - diagnosis; Breast Neoplasms - metabolism; Breast Neoplasms - surgery; Carcinoma, Ductal, Breast - diagnosis; Carcinoma, Ductal, Breast - metabolism; Carcinoma, Ductal, Breast - surgery; Clinical Decision-Making; Female; Humans; Immunohistochemistry; Neoplasm Staging; Prognosis; breast cancer; MUC1; cyclin; Atypical ductal hyperplasia; Ki67; biomarker

Atypical Ductal Hyperplasia (ADH) is a disease of the proliferative breast lesion characterized with atypia and when diagnosed on core needle biopsy (CNB), excisional biopsy is the current management to exclude adjacent cancer, which may found 10 to 20%. The purpose of the study is to investigate th...