Clostridioides difficile Infection: A Clinical Review of Pathogenesis, Clinical Considerations, and Treatment Strategies

• Published in: Curēus (Palo Alto, CA) Vol. 15; no. 12; p. e51167
• Main Authors: Sinnathamby, Evan S, Mason, Joseph W, Flanagan, Chelsi J, Pearl, Nathan Z, Burroughs, Caroline R, De Witt, Audrey J, Wenger, Danielle M, Klapper, Vincent G, Ahmadzadeh, Shahab, Varrassi, Giustino, Shekoohi, Sahar, Kaye, Alan D
• Format: Journal Article
• Language: English
• Published: United States Cureus Inc 27.12.2023
• Subjects: Abdomen; Antibiotics; Antigens; Asymptomatic; Chronic obstructive pulmonary disease; Cytotoxicity; Diagnostic tests; Diarrhea; Hospitals; Infections; Inflammation; Inflammatory bowel disease; Laboratories; Microbiota; Mortality; Patients; Peritonitis; Toxins; cholestyramine; colitis; nosocomial; ileostomy; fecal transplant; endoscopy; diarrhea; intravenous immunoglobulin

infection (CDI) is a common nosocomial infection. Risk factors for developing CDI include prior hospitalization, being older than 65 years old, antibiotic use, and chronic disease. It is linked with diarrhea and colitis and can vary in severity. It is a major cause of increased morbidity and mortali...