Expression of hnRNP A2/B1 proteins in human cancer cell lines
The overexpression of heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 is recently reported informative as a marker of lung cancer for early detection. To examine whether the expression of the proteins is specific for lung cancer, immunological analyses were performed both in lung and non-lung...
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| Published in | International journal of oncology Vol. 16; no. 4; p. 763 |
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| Main Authors | , , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
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01.04.2000
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| Abstract | The overexpression of heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 is recently reported informative as a marker of lung cancer for early detection. To examine whether the expression of the proteins is specific for lung cancer, immunological analyses were performed both in lung and non-lung cancer cell lines. In immunostaining and Western blotting, the expression of A2/B1 was observed not only in the lung cancer cells but also in non-lung cancer cells. The expression of hnRNP A2/B1 is not specific for lung cancer and quantitative determination of A2/B1 is required to elucidate their significance in carcinogenesis. |
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| AbstractList | The overexpression of heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 is recently reported informative as a marker of lung cancer for early detection. To examine whether the expression of the proteins is specific for lung cancer, immunological analyses were performed both in lung and non-lung cancer cell lines. In immunostaining and Western blotting, the expression of A2/B1 was observed not only in the lung cancer cells but also in non-lung cancer cells. The expression of hnRNP A2/B1 is not specific for lung cancer and quantitative determination of A2/B1 is required to elucidate their significance in carcinogenesis. |
| Author | Yamashita, Y T Ohtsuka, M Kamma, H Satoh, H Fujiwara, M Sekizawa, K Horiguchi, H Ishikawa, H |
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| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/10717246$$D View this record in MEDLINE/PubMed |
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| Snippet | The overexpression of heterogeneous nuclear ribonucleoprotein (hnRNP) A2/B1 is recently reported informative as a marker of lung cancer for early detection. To... |
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| SubjectTerms | Heterogeneous-Nuclear Ribonucleoprotein Group A-B Heterogeneous-Nuclear Ribonucleoproteins Humans Immunoblotting Lung Neoplasms - chemistry Microscopy, Fluorescence Neoplasms - chemistry Ribonucleoproteins - analysis Tumor Cells, Cultured |
| Title | Expression of hnRNP A2/B1 proteins in human cancer cell lines |
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