Analysis of a cell-free DNA–based cancer screening cohort links fragmentomic profiles, nuclease levels, and plasma DNA concentrations - Malki, Yasine; Kang, Guannan; Lam, W.K. Jacky; Zhou, Qing; Cheng, Suk Hang; Cheung, Peter P.H.; Bai, Jinyue; Chan, Ming Lok; Lee, Chui Ting; Peng, Wenlei; Zhang, Yiqiong; Gai, Wanxia; et al. (Genome research, 2025)
Keywords: Adult; Aged; Biopsy; Cancer screening; Cell-Free Nucleic Acids - blood; Cell-Free Nucleic Acids - genetics; Cohort Studies; Deoxyribonucleic acid; DNA; Early Detection of Cancer - methods; Endodeoxyribonucleases - blood; Female; Fetuses; Humans; Male; Middle Aged; Neoplasms - blood; Neoplasms - diagnosis; Neoplasms - genetics; Nuclease; Plasma; Tumors