A multi-treatment two stage allocation design for survival outcomes with nonrandom censoring: a copula-based approach

• Published in: Sequential analysis Vol. 43; no. 4; pp. 461 - 476
• Main Authors: Das, Soumyadeep, Bhattacharya, Rahul, Shome, Madhumita
• Format: Journal Article
• Language: English
• Published: Philadelphia Taylor & Francis 01.10.2024; Taylor & Francis Ltd
• Subjects: Asymptotic methods; Asymptotic p-value; Clayton copula; nonrandom censoring; Randomization; Statistical tests; Survival; Survival analysis; survival trials; two-stage adaptive design

In the context of clinical trials, a multi-treatment two-stage adaptive randomization procedure is developed for survival responses with copula-based nonrandom censoring. Because no such allocation design is available for survival responses with nonrandom censoring, this is probably the first work i...