Spiralian quartet developmental potential is regulated by specific localization elements that mediate asymmetric RNA segregation

• Published in: Development (Cambridge) Vol. 137; no. 23; pp. 4039 - 4049
• Main Authors: Rabinowitz, Jeremy S, Lambert, J David
• Format: Journal Article
• Language: English
• Published: England 01.12.2010
• Subjects: Animals; Base Sequence; Centrosome - metabolism; Embryo, Nonmammalian - cytology; Embryo, Nonmammalian - metabolism; Gene Expression Regulation, Developmental; Gene Knockdown Techniques; Larva - cytology; Larva - metabolism; Molecular Sequence Data; Nucleic Acid Conformation; Phenotype; Regulatory Sequences, Ribonucleic Acid - genetics; RNA - chemistry; RNA - genetics; RNA Transport; RNA, Messenger - genetics; RNA, Messenger - metabolism; Snails - cytology; Snails - embryology; Snails - genetics

Spiralian embryos are found in a large group of invertebrate phyla but are largely uncharacterized at a molecular level. These embryos are thought to be particularly reliant on autonomous cues for patterning, and thus represent potentially useful models for understanding asymmetric cell division. Th...