Modeling lesion transition dynamics to clinically characterize patients with clade I mpox in the Democratic Republic of the Congo

• Published in: Science translational medicine Vol. 17; no. 805; p. eads4773
• Main Authors: Nishiyama, Takara, Miura, Fuminari, Jeong, Yong Dam, Nakamura, Naotoshi, Park, Hyeongki, Ishikane, Masahiro, Yamamoto, Shotaro, Iwamoto, Noriko, Suzuki, Michiyo, Sakurai, Ayana, Aihara, Kazuyuki, Watashi, Koichi, Hart, William S, Thompson, Robin N, Yasutomi, Yasuhiro, Ohmagari, Norio, Kingebeni, Placide Mbala, Huggins, John W, Iwami, Shingo, Pittman, Phillip R
• Format: Journal Article
• Language: English
• Published: United States 02.07.2025
• Subjects: Adolescent; Adult; Democratic Republic of the Congo - epidemiology; Disease Outbreaks; Female; Humans; Male; Middle Aged; Models, Theoretical; Mpox, Monkeypox - epidemiology; Mpox, Monkeypox - pathology; Mpox, Monkeypox - virology; Viral Load; Democratic Republic of the Congo

Coinciding with the global outbreak of clade IIb mpox virus (MPXV), the Democratic Republic of the Congo (DRC) recently experienced a rapid surge in mpox cases with clade I MPXV. On 14 August 2024, the World Health Organization declared the continued cross-border spread of this clade in Africa a pub...