An specific photoelectrochemical sensor based on pillar[5]arenes functionalized gold nanoparticles and bismuth oxybromide nanoflowers for bovine hemoglobin recognition

• Published in: Journal of colloid and interface science Vol. 620; pp. 187 - 198
• Main Authors: Wang, Jin, Zhou, Lin, Bei, Jiali, Xie, Mengyuan, Zhu, Xiting, Chen, Tingting, Wang, Xiaomei, Du, Yukou, Yao, Yong
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 15.08.2022
• Subjects: Au@WP5/BiOBr nanoflowers; Biosensing Techniques; Bismuth - chemistry; Bovine hemoglobin; Dopamine; Electrochemical Techniques; Gold - chemistry; Hemoglobins; Limit of Detection; Metal Nanoparticles - chemistry; Photoelectrochemistry; Photoelectrochemistry; Dopamine; Bovine hemoglobin; Au@WP5/BiOBr nanoflowers
• ISSN: 0021-9797; 1095-7103
• DOI: 10.1016/j.jcis.2022.04.014

[Display omitted] •An ultrasensitive photoelectrochemical (PEC) was fabricated based on pillar[5]arenes functionalized Au and BiOBr nanoflowers (Au@WP5/BiOBr).•The immunosensor is specifically in bovine hemoglobin (BHb) sensing.•The COOH groups in BHb molecules formed a hydrogen bond with the NH2 groups of DA, achieving an indirect detection of BHb.•The LSPR effect of Au NPs, the host–guest interaction between WP5 and DA, the photo generated electron-holes of BiOBr nanoflowers are responsible for the enhanced PEC performance.•The proposed sensor displays ultralow detection limit. In this work, the ultrasensitive photoelectrochemical (PEC) sensor for the detection of bovine hemoglobin (BHb) was developed based on water-soluble pillar[5]arenes (WP5) functionalized gold nanoparticles (Au NPs) and bismuth oxybromide (BiOBr) nanoflowers (Au@WP5/BiOBr). The photoelectrical signal of dopamine (DA) was decreased after adding the different concentrations of BHb due to the formation of hydrogen bond between the COOH groups of BHb molecules and the NH2 group of DA, which could achieve the indirect detection of BHb. Benefiting from the photo-generated electron-holes of BiOBr nanoflowers, the localized surface plasmon resonance (LSPR) effect of Au NPs, the host–guest interaction of WP5 between and DA, the PEC sensor showed a specificallyrecognize toward BHb with a wide detection range of 1.0 × 10−11–1.0 × 10−1 mg/mL and a detection limit of 4.2 × 10−12 mg/mL (S/N = 3). Additionally, the proposed PEC sensor also displayed good stability, remarkable selectivity and provided a promising strategy of design pillar[5]arenes functionalized photoelectric activity nanomaterials for PEC sensing application.