Hemophagocytic lymphohistiocytosis associated with acute otitis media: A case report

• Published in: Medicine (Baltimore) Vol. 103; no. 25; p. e38616
• Main Authors: Chung, Da Hyun, Lee, Kyu-Yup, Kim, Ji-Yoon, Jung, Da Jung
• Format: Journal Article
• Language: English
• Published: United States Lippincott Williams & Wilkins 21.06.2024
• Subjects: Acute Disease; Child, Preschool; Clinical Case Report; Cyclosporine - administration & dosage; Cyclosporine - therapeutic use; Dexamethasone - administration & dosage; Dexamethasone - therapeutic use; Etoposide - administration & dosage; Etoposide - therapeutic use; Humans; Immunoglobulins, Intravenous - therapeutic use; Lymphohistiocytosis, Hemophagocytic - complications; Lymphohistiocytosis, Hemophagocytic - diagnosis; Lymphohistiocytosis, Hemophagocytic - drug therapy; Lymphohistiocytosis, Hemophagocytic - etiology; Male; Otitis Media - complications; Otitis Media - drug therapy

Hemophagocytic lymphohistiocytosis (HLH) is a potentially life-threatening syndrome for which early recognition and treatment are essential for improving outcomes. HLH is characterized by uncontrolled immune activation leading to fever, cytopenias, hepatosplenomegaly, coagulation abnormalities, and...