Coexistent HCN4 and GATA5 Rare Variants and Atrial Fibrillation in a Large Spanish Family

• Published in: Canadian journal of cardiology Vol. 40; no. 7; pp. 1270 - 1280
• Main Authors: Fraile, Alfonso, Cebrián, Jorge, Thuissard-Vasallo, Israel, Pérez-Martín, Sara, Casado, Raquel, Gil-Fournier, Belén, Alonso-Martín, Joaquín, Tamargo, Juan, Caballero, Ricardo, Delpón, Eva, Cosío, Francisco G.
• Format: Journal Article
• Language: English
• Published: England Elsevier Inc 01.07.2024

Familial association of atrial fibrillation (AF) can involve single gene variants related to known arrhythmogenic mechanisms; however, genome-wide association studies often disclose complex genetic variants in familial and nonfamilial AF, making it difficult to relate to known pathogenetic mechanism...