Generating neurons from stem cells

• Published in: Methods in molecular biology (Clifton, N.J.) Vol. 438; p. 31
• Main Authors: Androutsellis-Theotokis, Andreas, Murase, Sachiko, Boyd, Justin D, Park, Deric M, Hoeppner, Daniel J, Ravin, Rea, McKay, Ronald D G
• Format: Journal Article
• Language: English
• Published: United States 2008
• Subjects: Animals; Cell Culture Techniques - methods; Cell Differentiation; Cell Survival; Cryopreservation; Dissection; Immunohistochemistry; Mice; Neurons - cytology; Rats; Stem Cells - cytology

Recent work shows that major developmental and clinical processes such as central nervous system regeneration and carcinogenesis involve stem cells (SCs) in the brain. In spite of this importance, the requirements of these SCs and their differentiated offspring (neurons, astrocytes, and oligodendroc...