SARS-CoV-2 Spike-specific T cell responses following COVID-19 vaccination in Japanese people living with HIV

• Published in: Japanese Journal of Infectious Diseases p. JJID.2025.086
• Main Authors: Ndubi, Mark, Toyoda, Mako, Ueno, Takamasa, Ngare, Isaac, Minami, Rumi, Motozono, Chihiro
• Format: Journal Article
• Language: English
• Published: Japan National Institute of Infectious Diseases 30.06.2025
• Subjects: Activation-induced marker assay; HIV-1; SARS-CoV-2; vaccine; HIV-1; SARS-CoV-2; vaccine; Activation-induced marker assay

Incompletely resolved immune dysfunction in people living with HIV (PLWH) on antiretroviral treatment (ART) could differentially impact CD4+ and CD8+ T cell subsets. In this study, we investigated SARS-CoV-2 vaccine-induced CD4+ and CD8+ T cell responses in 26 PLWH on ART following third-dose mRNA v...