Efficacy, Safety, and Future of GLP-1 Receptor Agonists: A Systematic Literature Review and Meta-Analysis

• Published in: Hormone and metabolic research Vol. 57; no. 5; p. 326
• Main Author: Katz, Griffin
• Format: Journal Article
• Language: English
• Published: Germany 01.05.2025
• Subjects: Diabetes Mellitus, Type 2 - drug therapy; Exenatide - adverse effects; Exenatide - therapeutic use; Glucagon-Like Peptide 1; Glucagon-Like Peptide-1 Receptor Agonists; Glucagon-Like Peptides - adverse effects; Glucagon-Like Peptides - analogs & derivatives; Glucagon-Like Peptides - therapeutic use; Glycated Hemoglobin - metabolism; Humans; Hypoglycemic Agents - adverse effects; Hypoglycemic Agents - therapeutic use; Immunoglobulin Fc Fragments - adverse effects; Immunoglobulin Fc Fragments - therapeutic use; Randomized Controlled Trials as Topic; Recombinant Fusion Proteins - adverse effects; Recombinant Fusion Proteins - therapeutic use; Treatment Outcome

GLP-1 receptor agonists have emerged as important therapeutic agents for type 2 diabetes mellitus (T2DM), but their comparative efficacy and broader applications remain subjects of ongoing research. The aim of the study was to evaluate and compare the efficacy, safety, and clinical applications of t...