Self-declared ethnicity and genomic ancestry in prostate cancer patients from Brazil

• Published in: Genetics and molecular research Vol. 15; no. 4
• Main Authors: Oliveira, J.S., Ferreira, R.S., Santos, L.M., Marin, L.J., Corrêa, R.X., Luizon, M.R., Simões, A.L., Gadelha, S.R., Sousa, S.M.B.
• Format: Journal Article
• Language: English
• Published: Brazil 17.10.2016
• Subjects: African Continental Ancestry Group - genetics; Aged; Brazil; Case-Control Studies; Ethnic Groups - genetics; European Continental Ancestry Group - genetics; Gene Frequency - genetics; Genome, Human; Humans; Male; Middle Aged; Neoplasm Grading; Pigmentation - genetics; Prostatic Neoplasms - genetics

Some studies of polymorphisms in prostate cancer (PCa) analyze individuals in a uniform manner, regardless of genetic ancestry. However, PCa aggressiveness differs between subjects of African descent and those of European extraction. Thus, genetic ancestry analysis may be used to detect population s...