Total neoadjuvant therapy versus standard neoadjuvant treatment strategies for the management of locally advanced rectal cancer: network meta-analysis of randomized clinical trials

• Published in: British journal of surgery Vol. 110; no. 10; pp. 1316 - 1330
• Main Authors: Donnelly, Mark, Ryan, Odhrán K, Ryan, Éanna J, Creavin, Ben, O’Reilly, Mary, McDermott, Ray, Kennelly, Rory, Hanly, Ann, Martin, Seán T, Winter, Des C
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 06.09.2023

Abstract Background This study compared the advantages and disadvantages of total neoadjuvant therapy (TNT) strategies for patients with locally advanced rectal cancer, compared with the more traditional multimodal neoadjuvant management strategies of long-course chemoradiotherapy (LCRT) or short-co...