Differential structure and immunomodulatory functions of lipophosphoglycan between Leishmania spp

• Published in: Immunology letters Vol. 268; p. 106885
• Main Authors: Teufel, Lisa U., Joosten, Leo A.B., dos Santos, Jéssica C.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier B.V 01.08.2024
• Subjects: Immunomodulation; Leishmania spp; Leishmaniasis; Lipophosphoglycan; Leishmaniasis; Immunomodulation; Lipophosphoglycan; Leishmania spp

•LPG has therapeutic potential as immunotherapy against leishmaniasis or cancer.•LPG-based vaccines may induce cell-mediated immunity against leishmaniasis.•Leishmania LPG is highly variable and has diverse immunomodulatory properties.•Variations in LPG shape host immune responses against Leishmania...