Optimization and Validation of an FTIR-based, All-in-one System for Viable MDR Bacteria Detection in Combat-related Wound Infection

• Published in: Military medicine Vol. 189; no. 11-12; p. e2421
• Main Authors: Chen, Ying, Leung, Andrew, Wang, Yulia, Archer, Nathan K
• Format: Journal Article
• Language: English
• Published: England 05.11.2024
• Subjects: Animals; Anti-Bacterial Agents - pharmacology; Anti-Bacterial Agents - therapeutic use; Disease Models, Animal; Drug Resistance, Multiple, Bacterial; Humans; Methicillin-Resistant Staphylococcus aureus - drug effects; Methicillin-Resistant Staphylococcus aureus - isolation & purification; Mice; Microbial Sensitivity Tests - methods; Spectroscopy, Fourier Transform Infrared - methods; Wound Infection - diagnosis; Wound Infection - microbiology
• ISSN: 1930-613X
• DOI: 10.1093/milmed/usae068

The U.S. Military members experiencing combat-related injuries have a higher chance of developing infections by multidrug-resistant (MDR) bacteria at admission to military hospitals. MDR wound infections result in higher amputation rates and greater risks for subsequent or chronic infections that re...