How Trustworthy is Light Transmittance Platelet Aggregometry With Low Platelet Count Samples? Insights From Test Replicates and Retrospective Analysis of Several Decades of Diagnostic Samples

• Published in: International journal of laboratory hematology
• Main Authors: Hayward, Catherine P. M., Al Dawood, Rabab, Wice, Lindsay, Moffat, Karen A.
• Format: Journal Article
• Language: English
• Published: England 23.06.2025
• Subjects: thrombocytopenia; platelet function tests; platelet aggregation

Light transmission platelet aggregometry (LTA) is useful to diagnose platelet function disorders (PFD). We evaluated the precision and reproducibility of LTA with low platelet count platelet-rich plasma (LPRP). LPRP maximal aggregation (MA) precision for informative agonists and LTA reproducibility...