Comparative Rates of Androgen Production and Metabolism in Caucasian and Chinese Subjects

• Published in: The journal of clinical endocrinology and metabolism Vol. 83; no. 6; pp. 2104 - 2109
• Main Author: Santner, S. J.
• Format: Journal Article
• Language: English
• Published: Bethesda, MD Endocrine Society 01.06.1998
• Subjects: 3-Oxo-5-alpha-Steroid 4-Dehydrogenase - metabolism; Adrenal Glands - metabolism; Androgens - biosynthesis; Androgens - metabolism; Androstenedione - metabolism; Asian Continental Ancestry Group; Biological and medical sciences; China - ethnology; European Continental Ancestry Group; Female; Glucocorticoids - urine; Gynecology. Andrology. Obstetrics; Humans; Ketosteroids - urine; Male; Male genital diseases; Medical sciences; Metabolic Clearance Rate; Sex Hormone-Binding Globulin - metabolism; Testosterone - metabolism; Tumors; United States; Asia; United States; North America; China; America; Prostate disease; Mongoloid; Metabolite; Pathogenesis; Sex hormone binding protein; Male; Glucocorticoid; Blood plasma; Adult; Female; Testicular hormone; Hormonal investigation; Male genital diseases; Human; Urine; Interconversion; Ethnic origin; Urinary system disease; Androgen; Steroid hormone; Ketosteroids; Malignant tumor; Testosterone; Adrenal hormone; Sex steroid hormone; Caucasoid; Prostate; Comparative study

Clinically apparent prostate cancer occurs more commonly among Caucasians living in Western countries than in Chinese in the Far East. Prior studies demonstrated diminished facial and body hair and lower levels of plasma 3 alpha-androstanediol glucuronide and androsterone glucuronide in Chinese than...