Choosing appropriate antidepressant therapy in the Elderly : A risk-benefit assessment of available agents

• Published in: Drugs & aging Vol. 13; no. 4; pp. 269 - 280
• Main Author: FLINT, A. J
• Format: Journal Article
• Language: English
• Published: Auckland Adis International 01.10.1998
• Subjects: Aged; Antidepressive Agents - chemistry; Antidepressive Agents - therapeutic use; Biological and medical sciences; Depression - drug therapy; Humans; Medical sciences; Neuropharmacology; Pharmacology. Drug treatments; Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease); Psychology. Psychoanalysis. Psychiatry; Psychopharmacology; Risk Assessment; Human; Amfebutamone; Serotonin; Psychotropic; Toxicity; MAO inhibitor; Nefazodone; Review; Tetracyclic compound; Trazodone; Catecholamine; Tricyclic compound; Reuptake inhibitor; Biological activity; Antidepressant agent; Venlafaxine; Elderly

This article discusses the advantages and disadvantages of tricyclic antidepressants (TCAs), tetracyclic antidepressants (i.e. mianserin), selective serotonin (5-hydroxytryptamine; 5-HT) reuptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs), triazolopyridines (i.e. trazodone), phenylpipe...