Tissue Factor Pathway-Driven Initial Thrombin Generation is Associated with Hypercoagulability in Obesity

• Published in: Thrombosis and haemostasis
• Main Authors: Kamikubo, Yuichi, Nagaya, Satomi, Inoue, Rina, Yamaguchi, Koichi, Morimoto-Kamata, Riyo, Inoue, Kenichi, Morishita, Eriko, Samad, Fahumiya, Ohkura, Naoki
• Format: Journal Article
• Language: English
• Published: Germany 31.03.2025

Initial thrombin (FIIa) generated via the tissue factor (TF) pathway plays a crucial role in amplifying coagulation. There is growing evidence that the TF pathway might contribute to hypercoagulation in obesity. However, it is unclear if the initial generation of FIIa (TG) is associated with hyperco...