Sensitivity of patient-specific physiological and pathological aortic hemodynamics to the choice of outlet boundary condition in numerical models

• Published in: Computer methods and programs in biomedicine update Vol. 7; p. 100194
• Main Authors: Wang, Tianai, Quast, Christine, Bönner, Florian, Zeus, Tobias, Kelm, Malte, Lemainque, Teresa, Steinseifer, Ulrich, Neidlin, Michael
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 2025; Elsevier
• Subjects: Aortic hemodynamics; Boundary conditions; Computational fluid dynamics; Patient-specific modeling; Sensitivity analysis; Boundary conditions; Aortic hemodynamics; Patient-specific modeling; Sensitivity analysis; Computational fluid dynamics
• ISSN: 2666-9900; 2666-9900
• DOI: 10.1016/j.cmpbup.2025.100194

•Near-wall hemodynamic parameters are insensitive to outlet boundary condition.•Bulk flow hemodynamic parameters depend strongly on outlet boundary conditions.•Outlet boundary conditions have larger effect in healthy than in pathological flow.•Proposition of boundary condition requirements for relia...