Intergenerational concordance of brain structure between depressed mothers and their never‐depressed daughters

• Published in: Psychiatry and clinical neurosciences Vol. 76; no. 11; pp. 579 - 586
• Main Authors: Minami, Fusaka, Hirano, Jinichi, Ueda, Ryo, Takamiya, Akihiro, Yamagishi, Mika, Kamiya, Kei, Mimura, Masaru, Yamagata, Bun
• Format: Journal Article
• Language: English
• Published: Melbourne John Wiley & Sons Australia, Ltd 01.11.2022; Wiley Subscription Services, Inc
• Subjects: Cognition; Cortex (cingulate); Cortex (frontal); Cortex (parietal); Cortex (temporal); Daughters; depression; family; Frontal gyrus; high risk; intergenerational transmission; Magnetic resonance imaging; Mental depression; Morphometry; Mothers; MRI; Neuroimaging; Substantia grisea; Superior parietal lobule; Temporal gyrus

Aim Parents have significant genetic and environmental influences, which are known as intergenerational effects, on the cognition, behavior, and brain of their offspring. These intergenerational effects are observed in patients with mood disorders, with a particularly strong association of depressio...