Congenital Cytomegalovirus Infection

• Published in: Journal for nurse practitioners Vol. 19; no. 4; p. 104563
• Main Authors: Zappas, Michelle P., O'Neill, Sharon P., Rotz, Courtney
• Format: Journal Article
• Language: English
• Published: Philadelphia Elsevier Inc 01.04.2023; Elsevier Limited
• Subjects: Case reports; Congenital diseases; congenital infection; Cytomegalovirus; Developmental disabilities; Developmentally delayed children; Eye contact; Families & family life; Hearing loss; human cytomegalovirus; Immunoglobulins; Infections; infectious disease; Magnetic resonance imaging; Medical prognosis; Medical screening; Microcephaly; neurodevelopmental delays; Newborn babies; Parents & parenting; Pediatrics; Sensorineural hearing loss; Viral infections; United States > US; sensorineural hearing loss; neurodevelopmental delays; congenital infection; infectious disease; human cytomegalovirus
• ISSN: 1555-4155; 1878-058X
• DOI: 10.1016/j.nurpra.2023.104563

Congenital cytomegalovirus (CMV) infection is the most common intrauterine infection and is the leading nongenetic cause of sensorineural hearing loss and neurodevelopmental delays in the pediatric population. Despite its high prevalence and significant sequelae, congenital CMV in the pregnant woman and neonate often goes undiagnosed. We present the case of a 23-month-old child presenting with developmental delays and bilateral sensorineural hearing loss as a result of CMV and describe with this case report the clinical features, diagnosis, testing, management, and prognosis of congenital CMV. •Congenital cytomegalovirus (CMV) is the most common congenital infection and the leading cause of nongenetic sensorineural hearing loss in children.•Congenital CMV is associated with cognitive deficits, developmental delays, and sensorineural hearing loss, but recognition is often delayed by parents and providers.•A case of congenital CMV infection resulting in neurodevelopmental delays and sensorineural hearing loss is presented.