T-wave depletion and bradycardia possibly secondary to acute pancreatitis: review of the literature

Acute pancreatitis has frequently been reported to be associated with transient electrocardiography changes mimicking myocardial infarction despite normal epicardial coronary arteries. Although the origin of these findings is poorly understood, suggested mechanisms have included electrolyte abnormal...

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Published inThe Turkish journal of gastroenterology Vol. 20; no. 4; pp. 295 - 297
Main Authors Türkay, Cansel, Aydoğan, Timuçin, Karanfil, Aydin, Uyar, Mehtap Erkmen, Selçoki, Yusuf, Kanbay, Mehmet
Format Journal Article
LanguageEnglish
Published Turkey Türk Gastroenteroloji Vakfı 01.12.2009
Subjects
Acute Disease
Bradycardia - diagnosis
Bradycardia - etiology
Electrocardiography
Female
Humans
Middle Aged
Pancreatitis - complications
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Abstract Acute pancreatitis has frequently been reported to be associated with transient electrocardiography changes mimicking myocardial infarction despite normal epicardial coronary arteries. Although the origin of these findings is poorly understood, suggested mechanisms have included electrolyte abnormalities, a vagally mediated reflex, coronary vasospasm, and myonecrosis because of the release of pancreatic proteolytic enzymes. We report a case of acute pancreatitis with new-onset electrocardiography changes and bradycardia despite no evidence of coronary artery disease. After resolution of inflammation in the pancreas, T-wave depletions in V1-V6 derivations in electrocardiography disappeared and the rhythm was sinus with 70/min. 201-Tl myocardial perfusion scintigraphy revealed no evidence of significant coronary artery disease.
AbstractList Acute pancreatitis has frequently been reported to be associated with transient electrocardiography changes mimicking myocardial infarction despite normal epicardial coronary arteries. Although the origin of these findings is poorly understood, suggested mechanisms have included electrolyte abnormalities, a vagally mediated reflex, coronary vasospasm, and myonecrosis because of the release of pancreatic proteolytic enzymes. We report a case of acute pancreatitis with new-onset electrocardiography changes and bradycardia despite no evidence of coronary artery disease. After resolution of inflammation in the pancreas, T-wave depletions in V1-V6 derivations in electrocardiography disappeared and the rhythm was sinus with 70/min. 201-Tl myocardial perfusion scintigraphy revealed no evidence of significant coronary artery disease.
Akut pankreatite eşlik eden geçici elektrokardiyografik değişiklikler daha önce literatürde pek çok kez bildirilmiştir. Altta ya-tan neden tam olarak anlaşılmasa da, elektrolit anormallikleri, vagal refleks, koroner vazospazm, ve pankreatik proteolitik enzimlerine bağlı miyonekroz üzerinde durulan mekanizmalardır. Biz burada akut pankreatitli bir hastada koroner arter hastalığı olmaksızın gelişen elektrokardiyografik değişiklikler ve bradikardiyi sunuyoruz. Tedavi sonrası pankreasta inflamasyonun gerilemesi ile elektrokardiyografide V1-V6 derivasyonlarındaki T dalga negatifliği düzeldi ve kalp hızı 70/dk, sinus ritmi oldu. Hastanın çekilen 201-Tl miyokard perfüzyon sintigrafisinde koroner arter hastalığı bulgusuna rastlanmadı. Acute pancreatitis has frequently been reported to be associated with transient electrocardiography changes mimicking myocardial infarction despite normal epicardial coronary arteries. Although the origin of these findings is poorly understood, suggested mechanisms have included electrolyte abnormalities, a vagally mediated reflex, coronary vasospasm, and myonecrosis because of the release of pancreatic proteolytic enzymes. We report a case of acute pancreatitis with new-onset electrocardiography changes and bradycardia despite no evidence of coronary artery disease. After resolution of inflammation in the pancreas, T-wave depletions in V1-V6 derivations in electrocardiography disappeared and the rhythm was sinus with 70/min. 201-Tl myocardial perfusion scintigraphy revealed no evidence of significant coronary artery disease.
Author Karanfil, Aydin
Aydoğan, Timuçin
Uyar, Mehtap Erkmen
Selçoki, Yusuf
Türkay, Cansel
Kanbay, Mehmet
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DocumentTitleAlternate Akut pankreatite bağlı EKG'de T dalgası çökmesi ve bradikardi: Literatürün gözden geçirilmesi
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Snippet Acute pancreatitis has frequently been reported to be associated with transient electrocardiography changes mimicking myocardial infarction despite normal...
Akut pankreatite eşlik eden geçici elektrokardiyografik değişiklikler daha önce literatürde pek çok kez bildirilmiştir. Altta ya-tan neden tam olarak...
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SubjectTerms Acute Disease
Bradycardia - diagnosis
Bradycardia - etiology
Electrocardiography
Female
Humans
Middle Aged
Pancreatitis - complications
Title T-wave depletion and bradycardia possibly secondary to acute pancreatitis: review of the literature
URI https://www.ncbi.nlm.nih.gov/pubmed/20084577
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