Giant congenital nevus and chronic progressive ascending hemiparesis (Mills syndrome). Report of a case

We describe the case of a 20 year old boy with a giant congenital nevus who developed a chronic progressive ascending hemiparesis. The association of the pigmented lesion with a focal neurological deficit is pathognomonic for neurocutaneous melanosis complicated by a leptomeningeal melanoma. MR imag...

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Bibliographic Details
Published inItalian journal of neurological sciences Vol. 13; no. 3; p. 259
Main Authors Frisoni, G B, Gasparotti, R, Di Monda, V
Format Journal Article
LanguageEnglish
Published Italy 01.04.1992
Subjects
Adult
Hemiplegia - etiology
Humans
Magnetic Resonance Imaging
Male
Melanosis - diagnosis
Nevus, Pigmented - complications
Nevus, Pigmented - congenital
Nevus, Pigmented - pathology
Skin Neoplasms - complications
Skin Neoplasms - congenital
Skin Neoplasms - pathology
Syndrome
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Summary:We describe the case of a 20 year old boy with a giant congenital nevus who developed a chronic progressive ascending hemiparesis. The association of the pigmented lesion with a focal neurological deficit is pathognomonic for neurocutaneous melanosis complicated by a leptomeningeal melanoma. MR imaging at 1.5 tesla ruled out such a possibility and showed a small aspecific pontine lesion along the route of the corticospinal tract. We discuss possible etiologies.
ISSN:0392-0461
1126-5442
DOI:10.1007/BF02224400