A Metabolomic Approach to Investigate the Effect of Phytonutrients on Proteostasis and Metabolic Pathways in Drosophila melanogaster

• Published in: Planta medica Vol. 90; no. 7-08; p. 512
• Main Authors: Mikropoulou, Eleni V, Evangelakou, Zoi, Trougakos, Ioannis P, Halabalaki, Maria
• Format: Journal Article
• Language: English
• Published: Germany 01.06.2024
• Subjects: Animals; Drosophila melanogaster - drug effects; Female; Male; Metabolic Networks and Pathways - drug effects; Metabolome - drug effects; Metabolomics; Phytochemicals - pharmacology; Plant Extracts - chemistry; Plant Extracts - pharmacology; Proteostasis - drug effects

The use of as a biological platform to study the effect of diet and food bioactives on the metabolome remains a highly unexplored subject. Aiming to establish alternative solutions for the investigation of nutritional interventions with bioactive natural products by employing LC-MS-based metabolomic...