Urinary elimination of salsolinol enantiomers in alcoholics

• Published in: Journal of neural transmission. General section Vol. 85; no. 1; p. 51
• Main Authors: Dostert, P, Strolin Benedetti, M, Dordain, G, Vernay, D
• Format: Journal Article
• Language: English
• Published: Austria 01.02.1991
• Subjects: Adult; Alcoholism - urine; Humans; Isoquinolines - pharmacokinetics; Isoquinolines - urine; Male; Middle Aged

The analysis of the urine from 6 chronic alcoholics showed that (R)- and (S)-salsolinol were detectable in 4 subjects, the R enantiomer was only found in one and that both enantiomers were under the limit of detection in another one. 1,2-Dehydrosalsolinol was present in the urine of all of them. The...