Artificial transmembrane ion channels from commercial surfactants

• Published in: Chemical communications (Cambridge, England) no. 38; pp. 3951 - 3953
• Main Authors: Iqbal, Khayzuran S. J., Allen, Marcus C., Fucassi, Flavia, Cragg, Peter J.
• Format: Journal Article
• Language: English
• Published: CAMBRIDGE Royal Soc Chemistry 01.01.2007
• Subjects: Calixarenes - chemistry; Chemistry; Chemistry, Multidisciplinary; Membranes, Artificial; Physical Sciences; Science & Technology; Sodium Channels - chemistry; Surface-Active Agents - chemistry; MOLECULAR-BASIS

Sodium ion transport across a phospholipid bilayer has been demonstrated by a new class of transmembrane ion channel mimetic compounds in which the filtering effect of a calixarene has been coupled to the membrane penetrating qualities of a commercial surfactant.