A phase change material packaged multifunctional nanoplatform integrating hydrogen peroxide self-supply and photothermal response for boosting synergistic chemodynamic and photothermal therapy

• Published in: New journal of chemistry Vol. 47; no. 33; pp. 15561 - 15568
• Main Authors: Pang, Kai, Pidamaimaiti, Guligena, Zhu, Yuxi, Sun, Da, Yu, Bingchen, Duanmu, Zheng, Wang, Fu, Wei, Xunbin
• Format: Journal Article
• Language: English
• Published: Cambridge Royal Society of Chemistry 21.08.2023
• Subjects: Anticancer properties; Apoptosis; Biocompatibility; Copper sulfides; Hydrogen peroxide; Hydroxyl radicals; Hyperthermia; Nanoparticles; Near infrared radiation; Phase change materials; Therapy; Tumors
• ISSN: 1144-0546; 1369-9261
• DOI: 10.1039/d3nj02341a

Chemodynamic therapy (CDT) has received widespread attention due to its selectivity and oxygen independence, and is an emerging therapeutic methodology aimed at converting hydrogen peroxide (H 2 O 2 ) into hydroxyl radicals (&z.rad;OH). Despite the overexpression of H 2 O 2 in solid tumors, the...