Anticancer activity of the ethanolic extract of Crateva nurvala bark against testosterone and MNU-induced prostate cancer in rats

• Published in: Chinese journal of natural medicines Vol. 10; no. 5; pp. 334 - 338
• Main Authors: GURU KUMAR, Dugganaboyana, PARVATHI, Vijayakumar, MEENAKSHI, Periasamy, RATHI, Muthaiyan Ahalliya, GOPALAKRISHNAN, Velliyur Kanniappan
• Format: Journal Article
• Language: English
• Published: Elsevier B.V 01.09.2012
• Subjects: acid phosphatase; anticarcinogenic activity; Antioxidants; bark; Crateva; Crateva nurvala; epithelial cells; epithelium; histopathology; lipid peroxidation; N-methyl-N-nitroso urea; N-methyl-N-nitrosourea; normal values; Prostate carcinogenesis; prostatic neoplasms; rats; seminal vesicles; Testosterone; Prostate carcinogenesis; Antioxidants; Testosterone; N-methyl-N-nitroso urea; Crateva nurvala

In the present study the anticancer activity of the ethanolic extract of Crateva nurvala bark was evaluated against testosterone and N-methyl-N-nitrosourea (MNU)-induced prostate cancer in male Wistar rats. Prostate cancer was induced in rats by the injection of testosterone for 3 d followed by inje...