Beneficial effects of quercetin on renal injury and oxidative stress caused by ciprofloxacin in rats A histological and biochemical study

• Published in: Human & experimental toxicology Vol. 35; no. 3; pp. 276 - 281
• Main Authors: Elbe, H, Dogan, Z, Taslidere, E, Cetin, A, Turkoz, Y
• Format: Journal Article
• Language: English
• Published: London, England SAGE Publications 01.03.2016; Sage Publications Ltd
• Subjects: Animals; Anti-Bacterial Agents - toxicity; Antibiotics; Antioxidants - pharmacology; Atrophy; Biochemistry; Catalase; Catalase - metabolism; Ciprofloxacin; Ciprofloxacin - toxicity; Congestion; Female; Glutathione; Glutathione - metabolism; Hemorrhage; Infiltration; Injuries; Kidney - drug effects; Kidney - metabolism; Kidney - pathology; Kidneys; Malondialdehyde; Malondialdehyde - metabolism; Necrosis; Oxidation; Oxidative stress; Oxidative Stress - drug effects; Quercetin; Quercetin - pharmacology; Rats; Rats, Wistar; Rodents; Stretching; Superoxide dismutase; Superoxide Dismutase - metabolism; Tubules; quercetin; Ciprofloxacin; oxidative stress; renal injury

Ciprofloxacin is a broad-spectrum quinolone antibiotic commonly used in clinical practice. Quercetin is an antioxidant belongs to flavonoid group. It inhibits the production of superoxide anion. In this study, we aimed to evaluate the effects of quercetin on renal injury and oxidative stress caused...