Advanced in vitro evaluation of drug-induced kidney injury using microphysiological systems in drug discovery and development - Arakawa, Hiroshi; Matsushita, Kohei; Ishiguro, Naoki (Drug metabolism and pharmacokinetics, 2025)
Keywords: Acute Kidney Injury - chemically induced; Animals; Cell Culture Techniques - methods; Drug Development - methods; Drug Discovery - methods; Drug-induced kidney injury; Humans; In vitro method; Induced Pluripotent Stem Cells; Kidney; Kidney Tubules, Proximal - drug effects; Kidney Tubules, Proximal - metabolism; Microphyiological system; Microphysiological Systems; Spheroid; Transporter; In vitro method; Spheroid; Transporter; Microphyiological system; Kidney; Drug-induced kidney injury