Usnic acid based thiazole-hydrazones as multi-targeting inhibitors of a wide spectrum of SARS-CoV-2 viruses

• Published in: New journal of chemistry Vol. 47; no. 43; pp. 19865 - 19879
• Main Authors: Yarovaya, Olga I, Filimonov, Aleksandr S, Baev, Dmitriy S, Borisevich, Sophia S, Chirkova, Varvara Yu, Zaykovskaya, Anna V, Mordvinova, Ekaterina D, Belenkaya, Svetlana V, Shcherbakov, Dmitriy N, Luzina, Olga A, Pyankov, Oleg V, Salakhutdinov, Nariman F
• Format: Journal Article
• Language: English
• Published: CAMBRIDGE Royal Soc Chemistry 06.11.2023; Royal Society of Chemistry
• Subjects: Binding sites; Chemical synthesis; Chemistry; Chemistry, Multidisciplinary; Glycoproteins; Hydrazones; Modelling; Physical Sciences; Protease; Proteins; Science & Technology; Severe acute respiratory syndrome coronavirus 2; Viral diseases; Viruses; DRUG; DERIVATIVES

Although the Covid-19 pandemic is officially over and the spread of coronavirus infection is no longer considered an international emergency, the virus continues to persist in the population, supporting the process of mutagenesis, which may lead to the emergence of more dangerous variants that can c...