Electrophoretic Determination of Formaldehyde in Human Urine: Application to Alzheimer’s Disease

• Published in: Analytical letters Vol. 51; no. 9; pp. 1358 - 1372
• Main Authors: Yi, Fan, Liu, Lin-Zhen, Zhang, Mei-Jiang, Wang, Ting-Ting, Ye, Jian-Nong, Chu, Qing-Cui, Huang, Dong-Ping
• Format: Journal Article
• Language: English
• Published: Abingdon Taylor & Francis Ltd 13.06.2018
• Subjects: Acids; Alzheimer's disease; Biomarkers; Diagnosis; Electrical measurement; Electrophoresis; Family medical history; Formaldehyde; Human wastes; Patients; Sensitivity analysis; Thiobarbituric acid; Urine

The primary clinical diagnosis of Alzheimer's disease is mainly based on medical history and neuropsychiatric inventory. It is urgent to seek biological indicators with better sensitivity and higher specificity to clinically diagnose and evaluate Alzheimer's disease. In this work, an elect...