Vitamin D receptor TaqI and ApaI polymorphisms: A comparative study in patients with Behçet’s disease and Rheumatoid arthritis in Tunisian population

• Published in: Cellular immunology Vol. 290; no. 1; pp. 66 - 71
• Main Authors: Tizaoui, Kalthoum, Kaabachi, Wajih, Ouled Salah, Marwa, Ben Amor, Amira, Hamzaoui, Agnès, Hamzaoui, Kamel
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.07.2014
• Subjects: Adult; Arthritis, Rheumatoid - genetics; Behcet Syndrome - genetics; Behçet’s disease; Case-Control Studies; Deoxyribonucleases, Type II Site-Specific; Erythema Nodosum - genetics; Female; Gene Frequency; Genetic Predisposition to Disease; Humans; Male; Middle Aged; Polymerase Chain Reaction; Polymorphism, Restriction Fragment Length; Polymorphism, Single Nucleotide; Receptors, Calcitriol - genetics; Rheumatoid arthritis; Risk; Tunisia; VDR gene polymorphism; Vitamin D; Vitamin D - analogs & derivatives; Vitamin D - blood; Vitamin D; Behçet’s disease; VDR gene polymorphism; Rheumatoid arthritis

•TaqI and ApaI VDR polymorphisms are significantly implicated in Behçet’s disease.•The association between TaqI polymorphism and Behçet’s disease risk is age-dependent.•TaqI and ApaI VDR polymorphisms are not associated with Rheumatoid arthritis risk. Recent genetic surveys have identified vitamin D...