A Pharmacometric Method for Quantitative Determination of Improvement in Body Composition and Characterization of the Exposure-Response Relationship during Treatment of Obesity with Tirzepatide

• Published in: Clinical pharmacology and therapeutics
• Main Authors: Chigutsa, Emmanuel, Her, Lucy, Ma, Xiaosu, Urva, Shweta, Schneck, Karen
• Format: Journal Article
• Language: English
• Published: United States 25.06.2025

About half of the world's population is living with overweight or obesity. Tirzepatide is an approved treatment for chronic weight management. We sought to characterize the exposure-response relationship for weight reduction in patients with overweight or obesity and quantify the associated cha...