Retrospective evaluation of LCP‐tacrolimus (Envarsus XR) dosing in de novo kidney transplant

• Published in: Clinical transplantation Vol. 37; no. 11; p. e15082
• Main Authors: Alzahrani, Mohammed, Belcher, Rachel M., Benken, Jamie, Valdepenas, Benito, Di Cocco, Pierpaolo, Kajavathanan, Mathula, Benken, Scott T.
• Format: Journal Article
• Language: English
• Published: Denmark 01.11.2023
• Subjects: renal; kidney transplant; tacrolimus; obesity; transplantation

Tacrolimus is known to exhibit significant inter- and intra-patient pharmacokinetic (PK) and pharmacodynamic (PD) variability regarding therapeutic response. LCP-tacrolimus (LCPT-Envarsus XR) was approved in 2018 for use as a de novo immunosuppressive agent in kidney transplants, but there is limite...