A large scale multicentre randomized, placebo-controlled subcutaneous house dust mite allergen immunotherapy (HDM SCIT) in allergic rhinitis: MITAR Study

• Published in: Asian Pacific journal of allergy and immunology Vol. 42; no. 3; pp. 233 - 245
• Main Authors: Suratannon, Narissara, Limsuwan, Ticha, Tantilipikorn, Pongsakorn, Chatchatee, Pantipa, Saengapaswiriya, Atik, Boonpiyathad, Tadech, Thongngarm, Torpong, Roongpuvapaht, Boonsam, Chantaphakul, Hiroshi, Kulalert, Prapasri, Thanaviratananich, Sanguansak, Sangsupawanich, Pasuree, Fooanant, Supranee, Manuyakorn, Wiparat, Chusakul, Supinda, Piboonpochanun, Orathai, Apornpong, Tanakorn, Wongpiyabovorn, Jongkonnee, Ruxrungtham, Kiat
• Format: Journal Article
• Language: English
• Published: Thailand The Allergy and Immunology Society 01.09.2024
• Subjects: Adolescent; Adult; Allergens - immunology; Allergic rhinitis; Animals; Antigens, Dermatophagoides - immunology; Child; Clinical trials; Dermatophagoides pteronyssinus - immunology; Desensitization, Immunologic - methods; Female; Hay fever; Humans; Immunoglobulin G4; Immunotherapy; Injections, Subcutaneous; Male; Medical treatment; Middle Aged; Placebos; Pyroglyphidae - immunology; Rhinitis; Rhinitis, Allergic - immunology; Rhinitis, Allergic - therapy; Treatment Outcome; Young Adult

Previous house dust mite subcutaneous immunotherapy (HDM SCIT) placebo-controlled trials have small sample sizes and lack a consensus on baseline treatment. To determine the efficacy of HDM SCIT in moderate-to-severe allergic rhinitis (AR) patients treated with an intranasal corticosteroid at baseli...