A Positive Association between a Western Dietary Pattern and High LDL-C among Iranian Population

• Published in: Journal of research in health sciences Vol. 20; no. 3; p. e00485
• Main Authors: Asadi, Zahra, Moghbeli, Meysam, Khayyatzadeh, Sayyed Saeid, Mohammadi Bajgiran, Maryam, Ghaffarian Zirak, Roshanak, Zare-Feyzabadi, Reza, Eidi, Marziyeh, bonakdar, Mahdi Taheri, Davari, Hafeze, Mahmoudi, Ali Asghar, Sheikh Andalibi, Nazanin, A.Ferns, Gordon, Ghazizadeh, Hamideh, Ghayour-Mobarhan, Majid
• Format: Journal Article
• Language: English
• Published: Hamadan University of Medical Sciences 25.07.2020
• Subjects: Original
• ISSN: 2228-7795; 2228-7809
• DOI: 10.34172/jrhs.2020.19

BACKGROUNDThe association between the presence of dyslipidemia and major dietary patterns was examined in an adult Iranian population. STUDY DESIGNA cross-sectional study. METHODSThis cross-sectional study was conducted among 4672 adults aged 35-65 yr old based on data from the Mashhad Stroke And Heart Atherosclerotic Disorder (MASHAD) Study initiated in 2010. Anthropometric and blood laboratory measurements were collected for all participants. Dietary intake was assessed using a validated 65-item food frequency questionnaire (FFQ). Dietary patterns were identified using factor analysis. RESULTSThe overall prevalence of dyslipidemia was 88% including elevated total cholesterol (38.9%), triglyceride (35.2%), low-density lipoprotein cholesterol (LDL-C) (35.3%) or decreased level of high-density lipoprotein cholesterol (HDL-C) (68.9%). After adjusting for potential confounding factors, participants with higher scores for a Western pattern with lower physical activity level and educational attainment, and higher current smoking habit, increased the risk of having a raised LDL-C (OR=1.17; 95% CI: 1.02, 1.34; P=0.02). However, there was no significant association between adherence to this dietary pattern and other types of dyslipidemia. There was no significant association between a balanced dietary pattern and dyslipidemia and its components (OR=0.90; 95% CI: 0.68, 1.18; P=0.431). CONCLUSIONDyslipidemia was more prevalent among individuals with higher consumption of a western dietary pattern. A direct association was found between adherence to Western dietary pattern and LDL-C level.