Local Anesthesia in Pediatric Patients – a Review of Current and Alternative Methods, Devices and Techniques

Besides its anesthetic properties, it also reduces the risk of bleeding due to the shrinkage of regional blood vessels without causing significant cardiovascular disturbance in healthy patients.11 The method allows dental clinicians to perform conservative dental manipulations requiring pulpal anest...

Full description

Saved in:
Bibliographic Details
Published inFolia Medica Vol. 60; no. 3; pp. 381 - 388
Main Authors Veneva, Elitsa R, Belcheva, Ani B
Format Journal Article
LanguageEnglish
Published Plovdiv MEDICAL UNIVERSITY- PLOVDIV 01.09.2018
Pensoft Publishers
Subjects
Online AccessGet full text

Cover

Loading…
Abstract Besides its anesthetic properties, it also reduces the risk of bleeding due to the shrinkage of regional blood vessels without causing significant cardiovascular disturbance in healthy patients.11 The method allows dental clinicians to perform conservative dental manipulations requiring pulpal anesthesia of maxillary frontal teeth, canines and premolars in adults and children weighing more than 40 kg.12,13 More studies on the effectiveness and safety of administration of the method for pediatric patients are necessary. 1.2. Safety precautions should be considered when intraligamentary anesthesia is applied on primary teeth close to developing permanent teeth, as some researchers report risk of enamel hypoplasia occurrence.26 An increasing number of clinical trials demonstrate measurable benefits of the technology.25,27 The effectiveness of the system in comparison to conventional syringe infiltration, in reducing dental anxiety and injection pain in pediatric patients, is a subject of clinical research with controversial results.24,28-30 b. Computer-assisted intraosseous anesthesia (CAIO) Intraosseous anesthesia is considered to be a successful alternative to conventional anesthetic infiltration by some authors, as the anesthetic agent is injected directly into the cancellous bone adjacent to the tooth required to be anesthetized.31 Computercontrolled intraosseous anesthesia delivered with constant velocity and pressure of the anesthetic solution, is found to reduce the injection pain and the time of onset of the anesthetic effect (Fig. 5). Virtual reality may also have analgesic potential47, leading to new term creation - "virtual anesthesia". [...]suggests that VR distraction may be a useful tool for dental clinicians and extensive research in this field is required to validate any efficacy of the method. Phentolamine mesylate (OraVerse) is a short-acting alpha-adrenergic antagonist, leading to an increased clearance of local anesthetic solution from the injection site, reducing the duration of action. Since it is an antagonist to the vasoconstrictor and not to the anesthetic agent compound, it is mainly recommended for use in non-surgical treatment.48 Controlled research reports high level of satisfaction of patients and dental practitioners.48-50 Despite its limitations, phentolamine mesylate is described as safe and effective means for reducing the duration of soft-tissue anesthesia induced by local anesthetic infiltration, and its associated functional deficits in adults and children after 6 years of age.50 CONCLUSION The safety and efficacy of the aforementioned products and techniques is a subject of current research studies.
AbstractList Painless treatment is an integral element of quality pediatric dental care. Recent progress in the field of local anesthesia has led to development of newer agents, delivery devices and also modification in injection techniques. Their aim is to allow the clinician a treatment approach associated with the improved pain control and reduced risk of adverse effect essential for pediatric patients. This article reviews available information on current and alternative means, methods and technologies for achieving local anesthesia in pediatric patients intended to minimize the pain associated with the procedure.
Besides its anesthetic properties, it also reduces the risk of bleeding due to the shrinkage of regional blood vessels without causing significant cardiovascular disturbance in healthy patients.11 The method allows dental clinicians to perform conservative dental manipulations requiring pulpal anesthesia of maxillary frontal teeth, canines and premolars in adults and children weighing more than 40 kg.12,13 More studies on the effectiveness and safety of administration of the method for pediatric patients are necessary. 1.2. Safety precautions should be considered when intraligamentary anesthesia is applied on primary teeth close to developing permanent teeth, as some researchers report risk of enamel hypoplasia occurrence.26 An increasing number of clinical trials demonstrate measurable benefits of the technology.25,27 The effectiveness of the system in comparison to conventional syringe infiltration, in reducing dental anxiety and injection pain in pediatric patients, is a subject of clinical research with controversial results.24,28-30 b. Computer-assisted intraosseous anesthesia (CAIO) Intraosseous anesthesia is considered to be a successful alternative to conventional anesthetic infiltration by some authors, as the anesthetic agent is injected directly into the cancellous bone adjacent to the tooth required to be anesthetized.31 Computercontrolled intraosseous anesthesia delivered with constant velocity and pressure of the anesthetic solution, is found to reduce the injection pain and the time of onset of the anesthetic effect (Fig. 5). Virtual reality may also have analgesic potential47, leading to new term creation - "virtual anesthesia". [...]suggests that VR distraction may be a useful tool for dental clinicians and extensive research in this field is required to validate any efficacy of the method. Phentolamine mesylate (OraVerse) is a short-acting alpha-adrenergic antagonist, leading to an increased clearance of local anesthetic solution from the injection site, reducing the duration of action. Since it is an antagonist to the vasoconstrictor and not to the anesthetic agent compound, it is mainly recommended for use in non-surgical treatment.48 Controlled research reports high level of satisfaction of patients and dental practitioners.48-50 Despite its limitations, phentolamine mesylate is described as safe and effective means for reducing the duration of soft-tissue anesthesia induced by local anesthetic infiltration, and its associated functional deficits in adults and children after 6 years of age.50 CONCLUSION The safety and efficacy of the aforementioned products and techniques is a subject of current research studies.
Author Veneva, Elitsa R
Belcheva, Ani B
Author_xml – sequence: 1
  givenname: Elitsa
  surname: Veneva
  middlename: R
  fullname: Veneva, Elitsa R
– sequence: 2
  givenname: Ani
  surname: Belcheva
  middlename: B
  fullname: Belcheva, Ani B
BookMark eNotj8tOwzAQRS0EEi2wZ2mJLYHxI4mzrMqrUhEV6j5y7Al1ldrFTovY8Q_8IV9CeKyuNPfoaO6YHPrgkZBzBldcluq6Dd0GbcaBqQyA5QdkxASTGWdSHJIRcJCZAimOyTilNUCRA-Qj4ufB6I5OPKZ-hclp6jxdoHW6j87Qhe4d-j7Rr49Pqukz7h2-0dDS6S7GoaDaWzrpeox-IPdIH7FfBZsu6c2AGky_wBLNyrvXHaZTctTqLuHZf56Q5d3tcvqQzZ_uZ9PJPDO8rFjG0LZl06oClOCobGOMLdrhYSFEjq0AmYOprMS2KDlKZkrFrRVgCqm5acQJmf1pbdDrehvdRsf3OmhX_x5CfKl17J3psNZ5xZQClByZRGMbZAyqRgtRQaW5GlwXf65tDD8T-noddsPcLtWc8VLklcgL8Q116Hcy
CitedBy_id crossref_primary_10_1109_JTEHM_2021_3090748
crossref_primary_10_4103_srmjrds_srmjrds_130_22
crossref_primary_10_1038_s41415_023_6063_7
crossref_primary_10_1038_s41432_024_01094_4
crossref_primary_10_1111_ipd_12936
crossref_primary_10_5604_01_3001_0016_0381
ContentType Journal Article
Copyright Copyright MEDICAL UNIVERSITY- PLOVDIV 2018
Copyright_xml – notice: Copyright MEDICAL UNIVERSITY- PLOVDIV 2018
DBID 3V.
4T-
4U-
7X7
7XB
88E
8FI
8FJ
8FK
ABUWG
AFKRA
BENPR
BYOGL
CCPQU
FYUFA
GHDGH
K9.
M0S
M1P
PHGZM
PHGZT
PJZUB
PKEHL
PPXIY
PQEST
PQQKQ
PQUKI
PRINS
DOA
DOI 10.2478/folmed-2018-0015
DatabaseName ProQuest Central (Corporate)
Docstoc
University Readers
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
ProQuest Central
East Europe, Central Europe Database
ProQuest One Community College
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Health & Medical Complete (Alumni)
Health & Medical Collection (Alumni)
Medical Database
ProQuest Central Premium
ProQuest One Academic (New)
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
DOAJ Directory of Open Access Journals
DatabaseTitle University Readers
ProQuest One Academic Middle East (New)
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest One Health & Nursing
ProQuest Central China
ProQuest Central
Health Research Premium Collection
Health and Medicine Complete (Alumni Edition)
Health & Medical Research Collection
ProQuest Central (New)
ProQuest Medical Library (Alumni)
ProQuest One Academic Eastern Edition
East Europe, Central Europe Database
ProQuest Hospital Collection
Health Research Premium Collection (Alumni)
ProQuest Hospital Collection (Alumni)
ProQuest Health & Medical Complete
ProQuest Medical Library
ProQuest One Academic UKI Edition
Docstoc
ProQuest One Academic
ProQuest One Academic (New)
ProQuest Central (Alumni)
DatabaseTitleList
University Readers
Database_xml – sequence: 1
  dbid: DOA
  name: DOAJ Directory of Open Access Journals
  url: https://www.doaj.org/
  sourceTypes: Open Website
– sequence: 2
  dbid: BYOGL
  name: East Europe, Central Europe Database
  url: https://proxy.k.utb.cz/login?url=https://search.proquest.com/eastcentraleurope
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
Dentistry
EISSN 1314-2143
EndPage 388
ExternalDocumentID oai_doaj_org_article_a591880e42e14ecdbe1109ba33909a28
GroupedDBID 0R~
29H
3V.
4.4
4T-
4U-
53G
5RE
5VS
7X7
7XB
88E
8FI
8FJ
8FK
8R4
8R5
AAFWJ
ABUWG
ACGFS
ADBBV
AFKRA
AFPKN
AHMBA
AIKXB
ALIPV
ALMA_UNASSIGNED_HOLDINGS
BAWUL
BCNDV
BENPR
BPHCQ
BVXVI
BYOGL
CCPQU
DIK
E0C
EJD
EMOBN
F5P
FYUFA
GROUPED_DOAJ
HMCUK
HZ~
IAO
K9.
KQ8
M1P
O9-
OK1
PHGZM
PHGZT
PJZUB
PKEHL
PPXIY
PQEST
PQQKQ
PQUKI
PRINS
PROAC
PSQYO
Q2X
RNS
SA.
SLJYH
UKHRP
ID FETCH-LOGICAL-c2791-1edf7bf860832e8dbccd6f0053335ef30450c9d4ef672e41c782dd30c64a2cb3
IEDL.DBID 7X7
ISSN 0204-8043
IngestDate Wed Aug 27 01:23:18 EDT 2025
Fri Jul 25 02:41:41 EDT 2025
IsDoiOpenAccess true
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 3
Language English
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c2791-1edf7bf860832e8dbccd6f0053335ef30450c9d4ef672e41c782dd30c64a2cb3
Notes ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 14
OpenAccessLink https://doaj.org/article/a591880e42e14ecdbe1109ba33909a28
PQID 2127359356
PQPubID 34374
PageCount 8
ParticipantIDs doaj_primary_oai_doaj_org_article_a591880e42e14ecdbe1109ba33909a28
proquest_journals_2127359356
PublicationCentury 2000
PublicationDate 2018-09-01
PublicationDateYYYYMMDD 2018-09-01
PublicationDate_xml – month: 09
  year: 2018
  text: 2018-09-01
  day: 01
PublicationDecade 2010
PublicationPlace Plovdiv
PublicationPlace_xml – name: Plovdiv
PublicationTitle Folia Medica
PublicationYear 2018
Publisher MEDICAL UNIVERSITY- PLOVDIV
Pensoft Publishers
Publisher_xml – name: MEDICAL UNIVERSITY- PLOVDIV
– name: Pensoft Publishers
SSID ssj0065005
Score 2.0810785
Snippet Besides its anesthetic properties, it also reduces the risk of bleeding due to the shrinkage of regional blood vessels without causing significant...
Painless treatment is an integral element of quality pediatric dental care. Recent progress in the field of local anesthesia has led to development of newer...
SourceID doaj
proquest
SourceType Open Website
Aggregation Database
StartPage 381
SubjectTerms Anesthesia
Anxiety
children analgesia
Clinical trials
Control theory
Dental care
Dentistry
Fear & phobias
Lasers
Local anesthesia
local anesthesia children
Methods
pain control pedodontics
Pain management
Patients
pediatric dental patients
pediatric dentistry anesthesia
Pediatrics
Studies
Teeth
Virtual reality
SummonAdditionalLinks – databaseName: DOAJ Directory of Open Access Journals
  dbid: DOA
  link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV3NSsQwEA6yJy-iqLi6yhw8GrZp058c1z8WUfGwwt5KmkxgQbpiV8--g2_okzhJuiJ48OK1tA3MTOabyUy-YeyUHB6K0kou0STcM8pxshvF06pSKAkvyTH7bov7Yvoob-b5_MeoL98TFumBo-DGOleeMoy-Q0H_sw16jsxGZ5SsK52Ga76EeTGZinXIVJbV2PmOfktGICruA4Oek_-Xyw04cr3NtvoAECZx4R22ge0ua289pMCE_A4FZN1Cw6KF7yka8BDJTzv4fP8ADfE8H5YOenYl0K2FyVN_tveGcBfmQndncInBE4QXZmu61m6Pza6vZhdT3k9C4CYtleACrSsbVxUUMKVY2cYYW7hwjzbL0flqZ2KUleiKMkUpDOG-tVliCqlT02T7bNAuWzxgEMqOWgpRYikLZxVlTIpQv1GJcQbtkJ17MdXPkeui9uzT4QHppO51Uv-lkyEbrYVc91uiqz2VfJarLC8O_2ONI7YZdevbvUZssHp5xWOKD1bNSTCFLw5Euzg
  priority: 102
  providerName: Directory of Open Access Journals
Title Local Anesthesia in Pediatric Patients – a Review of Current and Alternative Methods, Devices and Techniques
URI https://www.proquest.com/docview/2127359356
https://doaj.org/article/a591880e42e14ecdbe1109ba33909a28
Volume 60
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV25TsQwELU4JKBBnOJcuaDE2hzO4Qot7KIVlwAt0nZRYo8REsoCAWr-gT_kS5hxvFAg0aRIUtnjN8-e5zeMHSDgQZgZKSToQJCjnMC4USLKcwUS8yUCM6ktrtLhnTwbJ2N_4NZ4WeUUEx1Qm4mmM_IuOZHHiYqT9OjpWVDXKKqu-hYas2yerMtI0pWNfzZcSD5aCWMUSERiGbdlykhmedeS4N9gjIS5IN7gLfv_ILJLM6crbNnzQ95rJ3SVzUC9xhb7pOmhtmxrbOHSV8PXWX1BiYj3EK2QxjUPJX-o-U_vDX7dWqY2_Ovjk5e8rQLwieXek4mXteG9R38i-A780nWTbg55Hxx-uB9GU5PXZoONTgejk6Hw_ROEjjIVihCMzSqbp0izIshNpbVJrbt9GydgqUYaaGUk2DSLQIYa2YIxcaBTWUa6ijfZXD2pYYtxV6wsZRhmkMnUGoX7LIVcoVKBthrMNjum0SueWoeMgjyr3YvJy33hl0BRJorM3zACIMTIMBWQ22lVxrEKVBnl22xvOvaFX0hN8TvtO_9_3mVL7WSS_GuPzb2-vME-8oXXquOCosPmjwdX17cdt-vG5_lN_g3di8JG
linkProvider ProQuest
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwzV3NTtwwEB7RRSpcoIUioLT1AW4NJI7z4wOHpVu6lF3KYSvRU5TYY4RAWUQWED3xDtx4Fd6mT9Jx4rRSK3FD4ppElpwZfzP2fP4GYJ0AD4NEC0-g8j2rKOeR30iPp6lEQfGSgNmyLQ7i_nfx9Sg6moL79i6MpVW2mFgDtR4re0a-ZZXIw0iGUewYlPt4c037s2p7r0fG3OB89_PoU99zLQQ8xRMZeAFqkxQmjSnT4JjqQikdm_oCahihsWVCX0kt0MQJRxEoCphah76KRc5VEdKwL2CaNhU86sD0zo9vXwYtzlNq0xAkuS8I50XYFEG5SNItY68TaPLAIPVsVuIaAvyH93UQ252Hh3b6DXfldPNyUmyqn_8oQz7P__MK5lzuzLqNs7-GKSwXYKZn-U62Zd0CvBw6psAilAMbpFmXkJxS3OokZycl-9OXhB02crIV-3V7x3LWVEjY2DCnV8XyUrPumTstvUI2rDttVx9ZD2tsrT8YtQK41RsYPcXEl6BTjktcBlYXcnMRBAkmIjZa0h5UUh5VSF8ZhXoFdqzts_NGPSSzet71g_HFcebgIcsjaYXxaHVgQKtGF2iVYIs8DKUvc56uwFpr9cyBTJX9Nfnq468_wEx_NBxkg72D_bcw27ilpcmtQWdycYnvKK-aFO-dgzPInthlfgMdjjBi
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV1Nb9QwEB2VIhUuCAqIQgEf4Ia1ieN8-FChhWXV0g_1sEh7ixJ7XFVC2dKUVtz4D_01_B1-CTOOUw5I3HpNoihynmeePeP3AN5QwMO0dFpqtIlkRTlJuDFSVZVBTfmSAjN3WxwVu1_052W-XINf41kYbqscY2II1G5leY98wkrkWW6yvJj42BZxPJu_P_sm2UGKK62jncYAkX38cUXLt35nb0b_-q1S80-Lj7syOgxIq0qTyhSdL1tfFUREFFautdYVPpxPzXL0XEVMrHEafVEq1KmlfOpclthCN8q2Gb32Dtyl70p5ipXLm7Ue8Z6he1IlmpKAzoYKqdJlNfF81sARPNNKMmWJbgH_JIOQ4eYP4UGkpmI6YOkRrGG3Cfdm3E7EjnCbsHEYC_GPoTvgHCimFCiJQfanjTjtxI3thzge1Fp78fvntWjEUIAQKy-iHJRoOiemX-Nm5CWKw2Bk3b8TMwyhKzywGPVl-yewuI2BfQrr3arDZyBCnbTRaVpiqQvvDC3xDNGU1iTWW3Rb8IFHrz4bxDlqlssOF1bnJ3WcfXWTG9adI_BhSqB0LbLQattkmUlMo6ot2B7Hvo5zuK__Iu75_2-_hg2CYn2wd7T_Au4P_5Wb0LZh_eL8O74k1nLRvgr4EFDfMh7_AETH_2M
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Local+Anesthesia+in+Pediatric+Patients+%E2%80%93+a+Review+of+Current+and+Alternative+Methods%2C+Devices+and+Techniques&rft.jtitle=Folia+medica+%28Plovdiv%29&rft.au=Veneva%2C+Elitsa+R&rft.au=Belcheva%2C+Ani+B&rft.date=2018-09-01&rft.pub=MEDICAL+UNIVERSITY-+PLOVDIV&rft.issn=0204-8043&rft.eissn=1314-2143&rft.volume=60&rft.issue=3&rft.spage=381&rft.epage=388&rft_id=info:doi/10.2478%2Ffolmed-2018-0015&rft.externalDBID=HAS_PDF_LINK
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0204-8043&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0204-8043&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0204-8043&client=summon