Modal gating in neuronal and skeletal muscle ryanodine-sensitive Ca2+ release channels

• Published in: The American journal of physiology Vol. 271; no. 1 Pt 1; p. C144
• Main Authors: Armisén, R, Sierralta, J, Vélez, P, Naranjo, D, Suárez-Isla, B A
• Format: Journal Article
• Language: English
• Published: United States 01.07.1996
• Subjects: Animals; Anura; Calcium - pharmacology; Calcium Channels - drug effects; Calcium Channels - metabolism; Chickens; Homeostasis; Ion Channel Gating; Kinetics; Models, Biological; Muscle, Skeletal - metabolism; Neurons - metabolism; Rabbits; Rats; Ryanodine - pharmacology; Time Factors

The bursting behavior of ryanodine-sensitive single Ca2+ release channels present in chicken cerebellum endoplasmic reticulum (ER), rat hippocampus ER, and frog and rabbit skeletal muscle sarcoplasmic reticulum was established. Unconditional dwell time distributions fitted by the maximum likelihood...