Options for Multiple Food Allergies — Food Avoidance or Pharmacologic Treatment?
Food allergy is common, affecting up to 8% of children and 10% of adults in the United States. 1,2 Hospital admission data for food-induced anaphylaxis have shown a clear increasing trend in the United States. 3 Food avoidance and use of rescue treatment if accidental exposure occurs are the only ad...
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| Published in | The New England journal of medicine Vol. 390; no. 10; pp. 946 - 948 |
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| Main Author | |
| Format | Journal Article |
| Language | English |
| Published |
United States
Massachusetts Medical Society
07.03.2024
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| Subjects | |
| Online Access | Get full text |
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| Abstract | Food allergy is common, affecting up to 8% of children and 10% of adults in the United States.
1,2
Hospital admission data for food-induced anaphylaxis have shown a clear increasing trend in the United States.
3
Food avoidance and use of rescue treatment if accidental exposure occurs are the only advice options we provide. Various forms of immunotherapy for treating food allergy have been investigated in the past decade. However, adverse reactions including anaphylaxis were found to be very common among patients receiving oral immunotherapy for food allergy.
4
Therefore, patients with severe food allergy, especially those who are allergic to multiple foods, . . . |
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| AbstractList | Food allergy is common, affecting up to 8% of children and 10% of adults in the United States.
1,2
Hospital admission data for food-induced anaphylaxis have shown a clear increasing trend in the United States.
3
Food avoidance and use of rescue treatment if accidental exposure occurs are the only advice options we provide. Various forms of immunotherapy for treating food allergy have been investigated in the past decade. However, adverse reactions including anaphylaxis were found to be very common among patients receiving oral immunotherapy for food allergy.
4
Therefore, patients with severe food allergy, especially those who are allergic to multiple foods, . . . Food allergy is common, affecting up to 8% of children and 10% of adults in the United States.1,2 Hospital admission data for food-induced anaphylaxis have shown a clear increasing trend in the United States.3 Food avoidance and use of rescue treatment if accidental exposure occurs are the only advice options we provide. Various forms of immunotherapy for treating food allergy have been investigated in the past decade. However, adverse reactions including anaphylaxis were found to be very common among patients receiving oral immunotherapy for food allergy.4 Therefore, patients with severe food allergy, especially those who are allergic to multiple foods, . . . |
| Author | Wong, Gary W.K. |
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| Cites_doi | 10.1001/jamanetworkopen.2018.5630 10.1016/j.jacig.2022.05.006 10.1542/peds.2018-1235 10.1111/pai.12908 10.1016/S0140-6736(19)30420-9 10.1056/NEJMoa022613 10.1056/NEJMoa2312382 |
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| References | Leung, DY, Sampson, HA, Yunginger, JW (r5) 2003; 348 Wood, RA, Chinthrajah, RS, Rudman Spergel, AK (r6) 2022; 1 Gupta, RS, Warren, CM, Smith, BM (r1) 2019; 2 Gupta, RS, Warren, CM, Smith, BM (r2) 2018; 142 Wood, RA, Togias, A, Sicherer, SH (r7) 2024; 390 Chu, DK, Wood, RA, French, S (r4) 2019; 393 Motosue, MS, Bellolio, MF, Van Houten, HK, Shah, ND, Campbell, RL (r3) 2018; 29 e_1_3_4_3_2 e_1_3_4_2_2 e_1_3_4_8_2 e_1_3_4_7_2 e_1_3_4_6_2 e_1_3_4_5_2 e_1_3_4_4_2 |
| References_xml | – volume: 1 start-page: 225 year: 2022 end-page: 232 ident: r6 article-title: Protocol design and synopsis: omalizumab as monotherapy and as adjunct therapy to multiallergen OIT in children and adults with food allergy (OUtMATCH). publication-title: J Allergy Clin Immunol Glob – volume: 393 start-page: 2222 year: 2019 end-page: 2232 ident: r4 article-title: Oral immunotherapy for peanut allergy (PACE): a systematic review and meta-analysis of efficacy and safety. publication-title: Lancet – volume: 390 start-page: 889 year: 2024 end-page: 899 ident: r7 article-title: Omalizumab for the treatment of multiple food allergies. publication-title: N Engl J Med – volume: 142 start-page: e20181235 issue: 6 year: 2018 end-page: e20181235 ident: r2 article-title: The public health impact of parent-reported childhood food allergies in the United States. publication-title: Pediatrics – volume: 2 start-page: e185630 issue: 1 year: 2019 end-page: e185630 ident: r1 article-title: Prevalence and severity of food allergies among US adults. publication-title: JAMA Netw Open – volume: 29 start-page: 538 year: 2018 end-page: 544 ident: r3 article-title: National trends in emergency department visits and hospitalizations for food-induced anaphylaxis in US children. publication-title: Pediatr Allergy Immunol – volume: 348 start-page: 986 year: 2003 end-page: 993 ident: r5 article-title: Effect of anti-IgE therapy in patients with peanut allergy. publication-title: N Engl J Med – ident: e_1_3_4_2_2 doi: 10.1001/jamanetworkopen.2018.5630 – ident: e_1_3_4_7_2 doi: 10.1016/j.jacig.2022.05.006 – ident: e_1_3_4_3_2 doi: 10.1542/peds.2018-1235 – ident: e_1_3_4_4_2 doi: 10.1111/pai.12908 – ident: e_1_3_4_5_2 doi: 10.1016/S0140-6736(19)30420-9 – ident: e_1_3_4_6_2 doi: 10.1056/NEJMoa022613 – ident: e_1_3_4_8_2 doi: 10.1056/NEJMoa2312382 |
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| Snippet | Food allergy is common, affecting up to 8% of children and 10% of adults in the United States.
1,2
Hospital admission data for food-induced anaphylaxis have... Food allergy is common, affecting up to 8% of children and 10% of adults in the United States.1,2 Hospital admission data for food-induced anaphylaxis have... |
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| SubjectTerms | Adolescent Medicine Allergens Allergens - immunology Allergy Anaphylaxis Anti-Allergic Agents - therapeutic use Antibodies Asthma Autoimmune Disease Clinical Medicine Clinical Medicine General Critical Care Critical Care General Drug dosages Elimination Diets - methods Environmental Health Hazards Food allergies Food Hypersensitivity - diet therapy Food Hypersensitivity - drug therapy Food Hypersensitivity - immunology Humans Immunoglobulin E - immunology Immunology Immunology General Immunotherapy Inflammatory Disease Outpatient-Based Clinical Medicine Patients Pediatrics Pediatrics General Pulmonary Quality of life T-Cells Teenagers |
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| Title | Options for Multiple Food Allergies — Food Avoidance or Pharmacologic Treatment? |
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