Tumor necrosis factor α1 (TNFα1) administration can disrupt barrier function and attenuate redox defense in midgut of red crucian carp (Carassius auratus red var)

• Published in: Reproduction and breeding Vol. 3; no. 4; pp. 208 - 218
• Main Authors: Huang, Jin-Fang, Xiong, Ning-Xia, Li, Shi-Yun, Li, Ke-Xin, Ou, Jie, Wang, Fei, Luo, Sheng-Wei
• Format: Journal Article
• Language: English
• Published: KeAi Communications Co. Ltd 01.12.2023
• Subjects: Crucian carp; Cytokines; Gene expression; Gut immunity

TNFα belongs to superfamily of tumor necrosis factor that can exert the pleiotropic effort in a large quantity of biological processes, including immune homeostasis, intracellular modulation and etiopathogenesis, but its regulatory role in mucosal immune regulation of fish is unclear. Currently, thi...